CONTENTS 



HAP. PAGE 



10. Effect of Folic Acid Deficiency in Man 495 



11. Metabolism of Folic Acid 503 



12. Intestinal Synthesis of Folic Acid 505 



13. Human and Animal Requirements of Folic Acid 506 



14. Pharmacology of Folic Acid 508 



15. Folic Acid in the Nutrition of Micro-organisms 509 



16. Folic Acid in Higher Plants 512 



17. Folic Acid in the Nutrition of Insects • 512 



18. Analogues of Folic Acid 513 



19. Function of Folic Acid 526 



IX. Vitamin B^a (Erythrotin) 



1. Introduction 530 



2. Isolation, Purification and Properties of Vitamin B12 532 



3. Estimation of Vitamin B12 534 



4. Occurrence of Vitamin B12 537 



5. Effect of Vitamin B12 on Animals and Man 538 



6. Vitamin Bjg and Micro-organisms 543 



X. /)-Aminobenzoic Acid 



1. Introduction 545 



2. Isolation of ^-Aminobenzoic Acid 548 



3. Estimation of ^-Aminobenzoic Acid 549 



4. Occurrence of ^-Aminobenzoic Acid in Foodstuffs 550 



5. Effect of ^-Aminobenzoic Acid Deficiency in Animals 551 



6. Effect of ^-Aminobenzoic Acid Deficiency in Man 553 



7. Metabolism of ^-Aminobenzoic Acid 554 



8. Pharmacology of ^-Aminobenzoic Acid 555 



9. ^-Aminobenzoic Acid in the Nutrition of Micro-organisms 555 



10. Effect of ^-Aminobenzoic Acid on Higher Plants 559 



11. ^-Aminobenzoic Acid Requirements of Insects 560 



12. Analogues of ^-Aminobenzoic Acid 560 



13. Function of ^-Aminobenzoic Acid 562 



XI. Inositol 



1. Introduction 564 



2. Isolation of Inositol 565 



3. Chemical Constitution and Synthesis of Inositol 565 



4. Properties of Inositol 568 



5. Estimation of Inositol 568 



6. Occurrence of Inositol 570 



7. Effect of Inositol Deficiency in Animals 572 



8. Effect of Inositol Deficiency in Man 575 



9. Human and Animal Requirements of Inositol 575 



10. Metabolism of Inositol 576 



11. Intestinal Synthesis of Inositol 577 



12. Inositol in the Nutrition of Micro-organisms 577 



13. Inositol in Higher Plants 57^ 



