ANEURINE (thiamine) 



in the rumen was derived from microbial growth and not by concen- 

 tration of the vitamin already present in the diet. On the other 

 hand, the nmien of a cow maintained on the same diet contained no 

 aneurine, but the milk contained 2 to 2-5 /xg. per g. The conclusion 

 was therefore reached that aneurine was not a dietary essential for 

 the rimiinant. A later report by Hunt et al.^'^ failed to confirm the 

 earlier result, since no evidence could be obtained that aneurine was 

 synthesised in the rumen of a steer, the amount present being less 

 than that present in the diet. This may have been due to the nature 

 of the diet, however, since on increasing the amount of maize or 

 carbohydrate in the feeding-stuff, the difference between the two 

 values tended to decrease. 



References to Section 15 



1. A. Theiler, H. H. Green and P. R. Viljoen, Rep. vet. Res. 5. Afr., 



1915, 3-4, 9. 



2. S. L. Bechdel, H. E. Honeywell, R. A. Dutcher and M. H. Knutsen, 



/. Biol. Chem., 1928, 80, 231. 



3. N. B. Guerrant, R. A. Dutcher and L. F. Tomey, ibid., 1935, 110, 



233 ; N. B. Guerrant, R. A. Dutcher and R. A. Brown, /. 

 Nutrition, 1937, 13, 305. 



4. T. B. Osborne and L. B. Mendel, Publ. Carnegie Inst., 1911, No. 



156, part 2, p. 59. 



5. L. S. Fridericia, Skand. Arch. Physiol., 1926, 49, s^ ; L. S. 



Fridericia, P. Freudenthal, S. Gudjonnsson, G. Johansen and N. 

 Schoubye, /. Hygiene, 1927-28, 27, 70. 



6. M. H. Roscoe, ibid., 103. 



7. P. M. Kon, A Bacteriological and Physiological Study of the Pheno- 



menon of Potato Starch Refection in the Rat, Ph.D. Thesis, Univ. 

 of Reading, 1935 ; P. M. Kon, S. K. Kon and A. T. R. Mattick, 

 /. Hygiene, 1938, 38, i ; S. K. Kon, Proc. Nutr. Soc, 1945, 3, 

 217. 



8. J. Taylor and U. Thant, Indian J. Med. Res., 1919, 16, 747. 



9. H. Madsen, Nature, 1939, 143, 981 ; E. L. Taylor, ibid., 1939, 143, 



982 ; A. Eden, ibid., 1940, 146, 36, 628. 



10. R. F. Light, L. J. Cracas, C. T. Olcott and C. N. Frey, /. Nutrition, 



1942, 24, 427. 



11. L. Wildemann, Biochem. Z., 1941, 308, 10. 



12. B. Alexander, G. Landwehr and F. Mitchell, /. Clin. Invest., 1946, 



25, 287. 



13. V. A. Najjar and L. E. Holt, Science, 1943, 98, 456 ; /. Amer. Med. 



Assoc, 1943, 123, 683. 



14. C. W. Denko, W. E. Grundy, J. W. Porter, G. H. Berryman, 



T. E. Friedemann and J. B. Youmans, Arch. Biochem., 1946, 10, 

 33 ; C. W. Denko, W. E. Grundy, N. C. Wheeler, C. R. Henderson, 

 G. H. Berryman, T. E. Friedemann and J. B. Youmans, ibid., 

 1946, 11, 109. 



80 



