NICOTINIC ACID (NIACIN) 



Somewhat different results were obtained following the injection of 

 nicotinic acid, nicotinamide and nikethamide (diethylnicotin amide). 

 The values (ftg.) found were : 



Thus all the species examined, except the guinea-pig, were able to 

 methylate either nicotinamide or nicotinic acid, but methionine 

 appeared to have no constant effect on the metabolism. Nicotinic 

 acid was aminated in man and in dogs, cats and rats, but not in 

 rabbits and guinea-pigs, whilst rabbits and guinea-pigs, but not the 



258 



