EFFECT OF DEFICIENCY IN ANIMALS 



of liver was only released by digestion with acid. Yeast contained 

 only small amounts of pyridoxal.^^ 



According to Kitzes et al.,^^ honey, pollen and royal jelly contain 

 10, 900 and 1000 /xg, of vitamin Bg per 100 g. respectively, whilst 

 M. H. Hay dak and L. S. Palmer ^^ reported an even higher value, 

 5000 /xg. per g. for royal jelly, and a value of 500 /u,g. per g. for bee 

 bread. Royal jelly is therefore the richest known natural source of 

 vitamin Bg, as well as of other components of the vitamin B complex. 



The following values were obtained for the vitamin Bg content of 

 beers : ^^ a modern beer, 0-5 ; a stout brewed in 1899, 0-5 ; and an 

 ale brewed in 1796, i-2 /xg. per ml. 



References to Section 8 



1. L. Siegel, D. Melnick and B. L. Oser, /. Biol. Chem., 1943, 149, 



361. 



2. E. E. Snell, ibid., 1945, 157, 491. 



3. H. A. Schneider, J. K. Ascham, B. R. Platz and H. Steinbeck, 



/. Nutrition, 1939, 18, 99. 



4. L. M. Henderson, H. A. Waisman and C. A. Elvehjem, ibid., 1941, 



21, 589- 



5. T. W. Conger and C. A. Elvehjem, /. Biol. Chem., 1941, 138, 555. 



6. L. J. Teply, F. M. Strong and C. A. Elvehjem, /. Nutrition, 1942, 



24, 167. 



7. L. Atkin, A. S. Schultz, W. L, Wilhams and C. N. Frey, Ind. Eng. 



Chem., Anal. Ed., 1943, 15, 141. 



8. R. J. Wilhams, R. E. Eakin and J. R. McMahan, Univ. Texas 



Publ., 1941, No. 4137. 



9. J. Bonner and R. Borland, Arch. Biochem., 1943. 2, 451. 



10. E. C. Barton-Wright, Biochem. J., 1945, 39, x. 



11. M. Swaminathan, Indian J. Med. Res., 1940, 28, 427; Nature, 



1940, 145, 780. 



12. A. M. Copping, Biochem. J., i943. 37, 12. 



13. H. A. Waisman and C. A. Elvehjem, Vitamin Content of Meat, 1941. 



14. S. H. Rubin and J. Scheiner, /. Biol. Chem., 1946, 162, 389. 



15. S. H. Rubin, J. Scheiner and E. Hirschberg, ibid., 1947, 167, 599- 



16. G. Kitzes, H. A. Schuette and C. A. Elvehjem, /. Nutrition, 1943, 



26, 241. 



17. M. H. Haydak and L. S. Palmer, /. Econ. Entomol, 1942, 36, 310- 



9. EFFECT OF VITAMm Be DEFICIENCY IN ANIMALS 



Although Gyorgy originally defined vitamin Bg as the fraction of 

 the vitamin B complex that cured dermatitis in rats, Gyorgy and 

 Eckardt subsequently found that the purified vitamin did not in fact 

 cure rat acrodynia, but only modified its symptoms (page 307). This 



Z^7 



