VITAMIN Bi2 (ERYTHROTIN) 



one method being based on measuring the growth rate of mice born of 

 mothers maintained on a purified diet, and the other on counteracting 

 the growth retardation of mice fed thyroid-active material. ^o The 

 growth of vitamin Bjg-depleted rats was used by Frost et al.^^ for the 

 assay of vitamin B^g with apparently good correlation with the micro- 

 biological assay method, but crystalline vitamin B^g according to B. 

 H. Ershoff 22 was ineffective in counteracting the growth retardation 

 of hyperthyroid rats. 



References to Section 3 



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536 



