INOSITOL 



mice. Inositol mono- and tetra-phosphoric esters had 5 and 2 % of 

 the potency of inositol for yeast. ^ 



^"COOH 



OH H0\ OH 



H\OH H 



H OH 



H OH H OH 



(HI) (IV) 



H OH 



(VI) 



H OH 



(Vni) 



When the six hydroxyl groups of inositol were replaced by chlorine 

 atoms to give hexachlorocyclohexane, the well-known insecticide, 

 lindane (page 578), the growth-promoting activity of the molecule 

 was lost completely and replaced by growth-inhibitory activity ; the 

 chloro-compound inhibited the growth of both yeast * and fungi.' 



References to Section 15 



1. D. W. Woolley. /. Biol. Chem., 1941, 140, 461. 



2. W. H. Schopfer, Helv. Chim. Acta, 1944, 27, 468. 



3. T. Posternak and F. Ravenna, Helv. Chim. Acta, 1947, 30, 441. 



5S0 



