VITAMINS Bio, Bji, Bi3 AND 6^4 



was prevented and growth was promoted by the addition to the diet 

 of arginine, glycine and cystine. There seems to be little justification, 

 therefore, for retaining " vitamin B4 " as a legitimate component of 

 the vitamin B complex, and we may therefore regard vitamins B3, 

 B4 and B5 as of historical interest only. 



References to Section 3 



1. R. R. Williams and R. E. Waterman, J. Biol. Chem., 1928, 78, 311. 



2. L. Randoin and R. Lecoq, Compt. rend., 1926, 182, 1408. 



3. C. W. Carter, H. W. Kinnersley and R. A. Peters, Biochem. J., 



1930, 24, 1764. 



4. W. H. Eddy, S. Gurin and J. C. Keresztesy, /. Biol. Chem., 1930, 



87, 729. 



5. J. R. O'Brien, Biochem. J., 1934, 28, 926. 



6. C. W. Carter, ibid., 933. 



7. C. W. Carter and J. R. O'Brien, ibid., 1935, 29, 2746 ; 1936, 30, 43 ; 



1937. 31, 2270. 



8. J. G. Lee and A. G. Hogan, Missouri Agric. Exp. Stat. Bull., 1942, 



342. 



9. V. Reader, Biochem. J., 1929, 23, 689 ; 1930, 24, 77, 1827 ; H. W. 



Kinnersley, J. R. O'Brien, R. A. Peters and V. Reader, ibid., 

 1933. 27, 225. 



10. C. A. Elvehjem and A. Arnold, Nature, 1936, 137, 109. 



11. O. L. Kline, C. A. Elvehjem and E. B. Hart, Biochem. J., 1936, 30, 



780. 



12. O. L. Kline, H. R. Bird, C. A. Elvehjem and E. B. Hart, /. Nutri- 



tion, 1936, 11, 515. 



13. R. L. Swank and O, A. Bessey, ibid., 1941, 22, 77. 



14. G. M. Briggs, T. D. Luckey, C. A. Elvehjem and E. B. Hart, /. 



Biol. Chem., 1943, 150, 11. 



4. VITAMINS Bio, B113 Bi3 AND B14 



In a paper published in 1943, Briggs et al.^ stated that chicks 

 required two new factors for proper feathering and growth, in addition 

 to those already recognised. These were named vitamins Bjq and 

 Bji respectively, these numbers being selected " because there are at 

 the present time nine vitamins of the B complex concerned in chick 

 nutrition, seven of which have been well established as necessary, 

 namely, thiamine, riboflavine, pantothenic acid, choline, nicotinic 

 acid, pyridoxine and biotin. The two other members, inositol and 

 folic acid, appear to be necessary for the chick." 



This explains the absence of any information in the literature 

 about vitamins B7, Bg and Bg which may have puzzled a good many 

 people ; these \dtamins have never, in fact, existed ! There is thus 



613 



