MISCELLANEOUS WATER-SOLUBLE GROWTH FACTORS 



and a low white cell count. The chick factor from cow manure com- 

 pletely relieved symptoms of zoopherin deficiency in rats, and fractions 

 from crude, but not " vitamin-free " casein, liver extract powder and 

 " fish solubles ", had similar properties. Zoopherin was not present 

 in dried yeast. It appears to be related to vitamin B^g. 



References to Section 6 



1. G. O. Kohler, C. A. Elvehjem and E. B, Hart, /. Nutrition, 1938, 



16, 445. 



2. M. D. Cannon and G. A. Emerson, ihid., 1939, 18, 155. 



3. G. J. Mannering, M. D. Cannon, H. V. Barki, C. A. Elvehjem and 



E. B. Hart, /. Biol. Chem., 1943, 151, loi. 



4. H. A. Sober, G. J. Mannering, M. D. Cannon, C. A. Elvehjem and 



E. B. Hart, /. Nutrition, 1942, 24, 503. 



5. D. W. WooUey, /. Biol. Chem., 1942, 143, 679. 



6. D. W. Woolley and H. Sprince, ibid., 1945, 157, 447. 



7. K. A. Kuiken, Univ. Pittsburgh Bull., 1944, 40, 142. 



8. D. M. Hegsted, J. J. Oleson, C. A. Elvehjem and E. B. Hart, 



/. Biol. Chem., 1940, 133, xli. 



9. H. E. Robinson, R. E. Gray, F. F. Chesley and L. A. Crandall, 



/. Nutrition, 1939, 17, 227. 



10. D. M. Hegsted, S. W. Hier, C. A. Elvehjem and E. B. Hart, /. 



Biol. Chem., 1941, 139, 863. 



11. G. M. Briggs, R. C. Mills, C. A. Elvehjem and E. B. Hart, ibid., 



1942, 144, 47. 



12. H, J. Almquist and E. L. R. Stokstad, Nature, 1936, 137, 581 ; 



/. Nutrition, 1937, 13, 339 ; H. J. Almquist, ibid., 1937, 14, 241 ; 

 Poultry Sci., 1938, 17, 155. 



13. H. R. Bird, C. A. Elvehjem and E. B. Hart, /. Biol. Chem., 1936, 



114, X ; H. R. Bird, O. L. Kline, C. A. Elvehjem, E. B. Hart 

 and J. G. Halpin, /. Nutrition, 1936, 12, 571. 



14. H. R. Bird and J. J. Oleson, /. Biol. Chem., 1938, 123, xi. 



15. H. J. Almquist, Science, 1938, 87, 538 ; H. J. Almquist and E. 



Mecchi, /. Biol. Chem., 1938, 126, 407. 

 15a. C. W. Mushett and W. H. Ott, Poultry Sci., 1949, 28, 850. 



16. C. A. Gary, A. M. Hartman, L. P. Dryden and G. D. Likely, Fed. 



Proc, 1946, 5, 128. 



17. L. M. Zucker, T. F. Zucker, V. Babcock and P. Hollester, Arch. 



Biochem., 1948, 16, 115. 



7. MISCELLANEOUS GROWTH FACTORS FOR 

 MICRO-ORGANISMS 



The factors so far discussed were discovered as the result of feeding 

 tests on laboratory animals. There are other factors, however, the 

 existence of which has been revealed by their ability to stimidate the 



620 



