THE HEMOFLAGELLATES 



71 



disease, between these and the New World 

 forms, or between L. tropica and L. dono- 

 vani infections. 



Diagnosis : The same methods are 

 used in diagnosing L. tropica as L. dono- 

 vaiii infections, except for the tissues ex- 

 amined. The parasites are usually abun- 

 dant in dry Oriental sore, but are scanty 

 in wet Oriental sore and New World muco- 

 cutaneous leishmaniosis. 



A skin test, the Montenegro intrader- 

 mal reaction, is used with considerable 

 success in diagnosing American muco- 

 cutaneous leishmaniosis. A suspension of 

 killed organisms from NNN culture is in- 

 jected intradermally. In positive cases, 

 an erythematous wheal appears in 48 hours 

 and lasts 4 or 5 days. A small sterile 

 papule which becomes vesicular or pustu- 

 lar develops in the center of the wheal. 



Treatment : Organic antimony com- 

 pounds are effective against cutaneous 

 leishmaniosis. The same ones are used 

 as for kala-azar. 



Control : The same measures used 

 to prevent kala-azar are effective against 

 cutaneous leishmaniosis. 



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