KEYS TO ANTIBIOTICS 



151 



d. 248 and o20 to o2r) in methanol 



e. 244 and 284 in methanol 



f. 245 and 27:) 



g. 24.-) to 2:)0 and 400 to 4:)0 



Substances for which three maxima of light al) 

 sorption have been reported 



a. Pentaenes; about 317, 333, and 3.")0 



b. Hexaenes; about 338, 3o7, and 378 



antibiotic ¥ 43 

 antibiotic l-81d-ls 

 diazomycins 

 ractinomycins 



pentaene antifungal antibi- 

 otics I and II 

 cryptocidin 

 flavacid 

 mediocidin 

 questiomycin A 



c. 240, 410, and 42.") in cyclohexane 



4. Substances which have been reported to have antibiotic F 416 

 only end-absorption in ultraviolet light lustericin 



5. Substances giving a red color at alkaline reac- 

 tion 



a. Heating with XaOH produces red color and camphomycin 

 a basic gas 



b. Greenish yf>llow; acti\'e mainly against 

 phages; gives inactixc red solutions at alka- 

 line reaction 



6. ^liscellaneous substances 

 a. Yellowish red to reddish ^■iolet substances 



antil)iotic l-81d-ls 

 chrvsomvcin 



t). Xonsulfur-containing polypeptide 

 c. Acidic substances 



ractmomycms 



microcins 



phytoactin 



phytostreptin 



nigericin 



cardicin 



duramvcin 



d. Acidic polypeptide 



II. Antibiotics active not only against fungi, but also against gram-positi\-e and gram- 

 negati\'e bacteria 



A. Substances for which one light-absorption maximum has been reported 



1. 235, with shoulders at 285 and 295 caerulomycin 



2. 244, with a shoulder at 2()3 and a plateau at streptovaricins 

 316; bright orange materials; yellow in acid 



solution, red-amber in alkaline solution 



3. 2()5 in water cellostatin 



4. 275 in 0. 1 N HCl or at 266 to 270 in 0. 1 .V Xa( )H blasticidin S 



5. 275 to 280 in ethanol; contains sulfur sulfocidin 



6. 293 in water violacetin 



7. 388 in ethanol thiolutin 



B. Substances for which two light-absorption maxima have been reported 



1. 232 and 370 in methanol; contains sulfur thioaurin 



2. 244 and 274 DON 



3. 266 and 285 in ethanol; water-insoluble base nybomycin 



4. 267 and 280, with an inflection at 256; very un- mycomycin 

 stable acid 



