DESCRIPTION.^ OF ANTIBIOTICS 



377 



nutrient solution: mustard (80 per centj, red clo- 

 ver (61 per cent), cucumber (54 per cent), and 

 wheat (46 per cent) (85). Celery and radish plants 

 are most sensitive, lettuce moderately sensitive, 

 and pea, pepper, and watermelon tolerant to con- 

 centrations of 1:25 (103). Not to.xic to cucumber, 

 tomato, barley, safflower, or sunflower seeds 

 soaked for 24 hours in 200 ng per ml (12), or to 

 wheat, white mustard, or red clover seeds soaked 

 in 25 ppm (35). Nutrient solutions containing 50 

 ppm are inhibitory to growth, but sprays of 200 

 ppm do not aflect growth or alkaloid content of 

 tobacco plants (109). Stiitiulation: Wheat root 

 growth is enhanced when grown in water contain- 

 ing low concentrations of streptomycin (48). 

 Fresh weight of tobacco plants grown in a nutrient 

 solution containing 10 ppm of streptomycin is 

 greater than the control (109). Stimulates the 

 virus-tumor tissue of Ruinex acetosa at 2 ppm or 

 below (27). 



Cells 



Least injurious doses for spleen and skin cells 

 in tissue culture are 155 to 310 and 210 to 415 Mg 

 per ml, respectively (75). Highest concentration 

 permitting epithelial cell migration in tissue cul- 

 ture is 3.6 mg per ml (131). Minimal concentration 

 causing degeneration of HeLa cells is 10 to 20 mg 

 per ml (119). To.xic to Alii inn cepa root cells at 

 >100 ppm (30). 



Utilization: Tuberculosis. Infections caused by 

 gram-positive and gram-negative bacteria, in- 

 cluding bacteremia, meningitis, tularemia, brucel- 

 losis, plague, and others (25). 



References: 



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