ANTIMICROBIAL AND ANTITUMOR ACTIVITIES 



83 



Table 32 



Sensitivity of pathogenic microorganisms to 

 streptomycin in vitro (Youmans and 

 Usher, 1949) 



Actinomycetes 



Bacillns anthracis 



Brucella abortus 



Br. meliiensis 



Br. .s»/s 



Donovania gran ulumuli.'i 



Erysipelothrix rhusio- 



pathiae 

 Hemophilus influenzae 

 H. pertussis 

 Klebsiella pneumoniae 

 Leptospira icterohaem- 



orrhagiae 



Sensitive 

 .1/. 



tuberculosis var. 



bovis 

 A'eisseria gonorrhoeae 

 N^ . meningitidis (A'. ///- 



traccllularis) 

 Pasteurella multocida 

 P. pestis 

 P. tularensis 

 Salmonella species 

 Sal. typhosa (Eberthella 



ti/phosa) 

 Shigella dysenteriae 

 Sh. paradysenteriae 



Listeria monocytogenes Streptobacillus monili- 



(Lislerella monocyto- form is 



genes) Veillonclla gazogenes 



Mycobacterium tubercu- 

 losis var. hominis 



Moderately sensitive 



Aerobacter aerogenes 



Alcaligenes faecalis 



Corynebacterium diph - 

 theriae 



Coxiella burnetii (Rick- 

 ettsia burneti) 



Diplococcus pneumoniae 



Escherichia coli 



Hemophilus ducreyi 



Malleomyces mallei 



Staphylococcus albus 



Staph, aureus 



Nocardia asteroides 



Proteus morganii 



Insensitive 



Pr. vulgaris 



Pseudomonas aerugi- 

 nosa (Bacillus pyo- 

 cyaneus) 



Rickettsia akari 



R. proivazekii 



R. typhi (R . uiooseri) 



Streptococcus, a hemo- 

 lytic 



Streptococcus. /3 hemo- 

 lytic 



Streptococcus faecalis 



Vibrio cholerae (V. 

 comma) 



Bacteroides fragilis 



Bade r (rides fundilifor- 

 mis 



Clostridium species 



Malleomyces pseudo- 

 uiatlei 



Rickettsia tsutsugamu- 

 shi (Rickettsia orien- 

 talis) 



Feline pneumonitis or- 

 ganism 



Virus of himian influ- 

 enza 



Psittacosis organism 

 Blastomyces dermatidi- 



iis 

 Candida albicans 

 ( 'occidioides im m it is 

 Cryptococcus neofor- 



utans (Torula histo- 

 lytica) 

 Geotrichum species 

 Histoplasma capsulatuui 

 Endauioeba histolytica 

 Trichomonas vaginalis 

 Trypauosoma species 



Table 32 — Continued 



Lymphogranu- 

 loma venereum 



Meningopneu- 

 monitis 



Virus of mumps 



Table 33 



Responses of bacteria to neomycin B, neomycin C, 



and neamine (Sel)ek, 1958) 



Organism 



Serratia marcescens 



Micrococcus pyogenes var. 



albus 



Bacillus brevis 



Corynebacterium diphthc- 



roides 



Neisseria catarrhalis 



Aerobacter aerogenes 



Klebsiella pneumoniae . . . 



Escherichia coli 



Micrococcus pyogenes var. 



aureus 



Shigella dysenteriae 



Salmonella paratyphi .... 



Proteus vulgaris 



Salmonella pullorum 



Shigella parody sen teriae 



var. sonnei 



Salmonella schdttnniclleri 



Sal. hirschfeldii 



Pseudomonas aeruginosa . 

 Streptococcus pyogenes. . . 

 Streptocoi-cus viridans. . . . 

 Diplococcus pneumoniae . 

 Alcaligenes faecalis 



Micrococcus lysodeiklicus 



Corynebacterium sp 



Sarcina lutea 



In the latter case, growth \voiild take place 

 in the presence of nutrients, after the anti- 

 biotic had been washed off the cells. 



The microbicidal action of antibiotics 



