KEYS TO ANTIBIOTICS 145 



7. 240, 305, 385, and 401 in methanol rifomyeins 



8. 269 to 270, 290, 820, 840, and 460 heliomyein 



resistomycin 



9. 294, 331, 471, and 529 in alkaline ethanol prodigiosin-like antibiotic 

 10. 504, 535, 542, and 575 in l)enzene rhodomycins 



E. Antibiotic with a pr(),<!;rcssi\(' drop in light absorption tVom 210 to 450 



("unphom^ycin 



F. Antibiotics ha^•ing no typical light-absorption spectra or for which light absorption 

 data were not reported 



1. Antibiotic active only against Sarcina lutea sarcidin 



2. Antibiotic actiA'C mainly against Coryncbacter- thermomycin 

 ium diphtheriae 



3. Antibiotic active only against respiratory-de- mntonrycin 

 ficient staphylococci 



4. Antibiotic active mainly against Streptococcus totomycin 

 hemolytic us 



5. Antibiotics presumably active against ^'ari<)us 

 gram-positive bacteria 



a. Water-soluble substances 



(1) Acidic substances streptocin 



duramycin 



(2) Neutral, yellowish green substance actinomycelin 



(3) Basic substances 



(a) Positive Sakaguchi and ninhydrin antibiotic AX 18 

 reactions 



(b) Positive Sakaguchi reaction, nega- antibiotic A 116 

 tive ninhydrin reaction cinnamycin 



(c) Negative Sakaguchi and ninhydi'in albomycetin 

 reaction amphomycin 



(d) Negative Sakaguchi reaction, posi- trehalosamine 

 tWe ninhydrin reaction 



(e) Unknown Sakaguchi and ninhydrin actinoidin, HCl salt 

 reactions 



(4) Polypeptide or proteinaceous substances actinoxanthine 



amphomycin 



cinnamycin 



crystallomycin 



duramycin 



micromonosporin 



phytostreptin 



(5) Red-amber substance, brilliant yellow antibiotic 721 

 solution at alkaline pH 



(6) Red-brown substance. Yellow in acidic antibiotic SKCC 1377 

 solutions, purple at alkaline pH 



b. Substances solul)le in water only at alkaline 

 reaction 



