DIFFERENTIAL CHARACTERS OF TUBERCLE BACILLI 

 TABLE 29 {continued). 



437 



5% 

 Glycerine 

 potato. 

 4 weeks 

 at 37° G. 



5% 

 Glycerine 

 broth. 

 8 weeks 

 at 37° G. 



Antigenic 

 structure 



Pathogeni- 

 city 



Luxuriant, 

 raised, con- 

 fluent, 

 cream- 

 coloured 

 growth, with 

 a nodular, 

 warty, or 

 worm-cast 

 surface 



Thick, white 

 or cream- 

 coloured, 

 duU, 

 wrinkled 

 pellicle, 

 extending 

 up the sides 

 of the flask ; 

 no turbidity: 

 slight granu- 

 lar or scaly 

 deposit 



Bovine. 



Poor, dis- 

 crete or 

 confluent, 

 thin, effuse, 

 greyish 

 growth 



Thin, greyish- 

 white film 

 over part of 

 surface, 

 sUghtly 

 nodular in 

 places. No 

 turbidity ; 

 slight finely 

 granular 

 deposit 



By aggluti- 

 nation, 

 absorption 

 of agglu- 

 tinins, and 

 complement, 

 fixation, 

 form a ' 



homogene- 

 ous group 



Natural dis- 

 ease in man, 

 pigs, mon- 

 keys, dogs 

 and parrots. 

 Experiment- 

 ally, patho- 

 genic for 

 guinea-pig 

 and for 

 mouse 



Indistin- 

 guishable 

 from the 

 human 

 group 



?, but good Sometimes 



growth on 

 plain potato 



Indistin- 

 guishable 

 from the 

 human 

 group 



Natural dis- Natural dis- 



similar to 



human type, 



but usually 



profuse, 



confluent, 



paint-Uke 



growth, with 



slightly 



nodular 



surface 



Sometimes 

 only a granu- 

 lar deposit at 

 the bottom ; 

 sometimes a 

 thick veil 

 over the 

 bottom of 

 the flask and 

 part- way up 

 the sides, 

 made up of 

 branching, 

 interlacing 

 columns, 

 like tripa. 

 No turbidity ; 

 no surface 



j growth 



Form a separ- 

 ate group 



ease in 

 bovines, 

 pigs, cats, 

 monkeys and 

 man. Ex- 

 perimentally, 

 pathogenic 

 for guinea- 

 pig, rabbit, 

 cat, mouse, 

 goat, vole, 

 and calf 



ease m 

 voles. Ex- 

 jjerimentally 

 pathogenic 

 for voles, 

 rats, mice 

 and to a 

 less degree 

 for golden 

 hamsters 



Cold-blooded. 



7 d. 22° G. 

 Profuse, 

 raised, con- 

 fluent, 

 cream- 

 coloured 

 growth, with 

 a coarsely 

 granular or 

 worm-cast 

 surface 



4 weeks 22° G. 

 No turbidity, 

 but thick 

 veil over the 

 bottom of the 

 flask and 

 part-way up 

 the sides, 

 made up of 

 coarse inter- 

 lacing 



columns ; no 

 surface 

 growth 



Form a separ- 

 ate group 



Natural dis- 

 ease in birds 

 and pigs. 

 Experiment- 

 ally, patho- 

 genic for 

 birds ; 

 moderately 

 pathogenic 

 for rabbits, 

 rats, and 



Natural dis- 

 ease in cold- 

 blooded 

 animals and 

 fish. Ex- 

 perimentally, 

 pathogenic 

 for turtles, 

 frogs, snails, 

 lizards, and 

 fish 



Saprophytic 

 jicid-fast. 



7 d. 22° G. or 

 37° G. Abun- 

 dant, raised, 

 confluent, 

 often pig- 

 mented 

 growth, with 

 coarsely 

 granular sur- 

 face, looking 

 like dry 

 bread- 

 crumbs. 



14 days 22° G. 

 or 37° G. 

 Thick, 

 coarsely 

 granular sur- 

 face pellicle, 

 looking as if 

 composed of 

 dry bread- 

 crumbs. 

 May be 

 yellowish- 

 white or 

 pink ; 

 spreads up 

 sides of flask. 

 No turbidity. 

 Deposit of 

 coarse 

 granules. 



Form a separ- 

 ate group — 

 probably 

 divided into 

 sub-groups. 



Non-patho- 

 genic. 



