666 NEISSERIA 



meningococcal serum (Jaeger 19036, c, Netter and Debre 1911, Dopter 1921). According 

 to von Lingelsheim (1906) an antimeningococcal serum agglutinates Dip. crassus almost 

 or quite to titre, whereas an anti-crassus serum agglutinates the meningococcus to only 

 ji__JL titre. According to Jaeger (1899) dried cultures remain aUve for 3 or 4 months. 



N. flavescens. — This organism was isolated by Branham (1930) from the spinal 

 fluid of a number of patients suffering from epidemic cerebrospinal meningitis. It 

 differs from the meningococcus chiefly in its production of pigment, its lack of 

 fermentative action, and its antigenic constitution. In the spinal fluid it appears 

 in the form of Gram-negative oval-shaped cocci arranged in flattened pairs ; 

 individual cells vary in size and depth of staining ; giant forms are common. The 

 organisms grow well on blood agar and semi-solid agar, but poorly on dextrose agar. 

 They produce a golden-yellow pigment. They are without fermentative action on 

 any of the usual carbohydrates. They are not agglutinated by type antimeningo- 

 coccal sera, but constitute among themselves a serologically homogeneous group. 

 Their ability to give rise under favourable conditions to meningitis appears to be 

 unquestioned. 



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