FRIEDLANDERS bacillus 681 



HjS — ; M.B. reduced ; catalase + + ; Koser's citrate + ; gas in MacConkey 

 broth at 44" C. negative. (For biochemical characters of rhinoscleroma and 

 ozsena strains, see p. 670). 



Antigenic Structure. — By agglutination, absorption, and precipitin tests there are three 

 types, A, B, and C of Friedlander's bacillus, and a heterogeneous group X. The 

 specificity of the types is determined by the carbohydrate fraction in the capsule. 

 The B type is similar immunologically to Type II pneumococcus. (For antigenic 

 structure of rhinoscleroma and ozsena strains, see p. 673). 



Pathogenicity. — Is found in lesions of the respiratory tract and in suppurative conditions 

 generally in the human body. Experimentally, it is highly pathogenic to mice 

 on intraperitoneal or intravenous injection. Rabbits are less susceptible, but often 

 succumb to intravenous or intraperitoneal injection. Types A and B are highly 

 virulent for mice ; Type C is avirulent. After intraperitoneal injection of a very 

 small quantity of broth culture mice die in 18 to 24 hours ; P.M. viscous exudate 

 in peritoneum ; capsulated bacilli numerous in blood, lungs and spleen. 



The Paracolon Group 



The organisms of this group, which diEFer from Bad. coli in fermenting lactose late, 

 weakly, irregularly, or not at all, and from the Salmonella and Shigella groups in fermenting 

 either lactose, sucrose, or salicin, in usually producing indole, and in their antigenic struc- 

 ture, have been described on pp. 676-8. 



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