784 PASTEU BELLA 



Pathogenicity. — No true exotoxin formed. Virulence subject to alteration. Causes pseudo- 

 tuberculosis in rodents, especially guinea-pigs. Experimental inoculation repro- 

 duces the disease in rodents. Subcutaneous injection of a 24-b.our broth culture 

 into a guinea-pig proves fatal in 1 to 3 weeks. P.M. caseous local swelling, enlarge- 

 ment of regional glands, and nodules in spleen, liver, and lungs. Microscopically 

 the bacilli are numerous in the local lesion and glands. 



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