INDEX— VOLUME II STARTS ON PAGE 971 



Anaphylactic shock, haptens, role of in, 1141 

 histamine shock, relation of to, 1141, 1148 

 humoral hypothesis of, 1 143 

 in the dog, 1138 

 in the guinea-pig, 1137, 1147 

 in the rabbit, 1138 

 in various animals, 1 139 

 induction period in, 1136 

 inhibition by antihistamine sera, 1150 

 by histaminase, 1150 

 by normal sera, 1148 

 mechanism of, 1142-1151 



cellular hypothesis of, 1145 

 Schultz-Dale technique in study of, 

 1146 

 passive sensitization in, 1140 

 peptone shock, relation of to, 1144 

 reversed passive anapiiylaxis in, 1 140 

 sensitization to, factors effecting, 1136 

 Anaphylactoid shock, 1144 

 Anaphjdatoxin, 1143 



Anaphylaxis, 1136-1151, 1156. See also 

 Allergy, Anaphylactic shock and H\'per- 

 sensitiveness 

 Arthus' phenomenon in, 1151 

 genetic factors in, 1159 

 local reactions in, 1151, 1156 

 relation of to immunity, 1146, 1164 

 Anatoxin. 1392 

 Angina, Vincent's, 914, 1810 

 Angular conjunctivitis, 898 

 Aniline dyes, effect of on bacteria. See Dyes 

 Animal diseases. See under name of disease 



and species of animal 

 Animal poxes. See Poxes, animal 

 Animals, anaerobic infections of. See Anae- 

 robic infections of animals 

 Anions, effect of on bacteria, 124 

 Antagonizers of chemotherapeutic agents, 159, 



161, 165, 166 

 Anthrax, 1730-1744 

 Ascoli test in, 1738 

 chemotherapy in, 1743 

 cutaneous, susceptibility to, 1183, 1184 

 diagnosis of, 1737 

 experimental production of in animals, 



1736 

 in animals, 1731, 1735 



infection of milk in, 1735, 1740 

 in man, 1733, 1735 

 local immunity to, 1184 

 mode of infection and spread, 1732 

 by earth-worms, 1732 

 by flics, 1733 

 by food-stuffs, 1732 

 natural immunity to, 1739 

 prevention of, 1740 

 serum treatment of, 1743 

 symptomatic. See Blackleg 

 vaccination against, 1740 

 wool-sorters' disease in, 1733, 1734 

 Antibacterial immunity. See Immunity, anti- 

 bacterial 

 Antibacterial index, 162 

 Antibacterial substances. 155, 172 

 from bacteria, 173, 174 

 froiPi moulds, 175 



Antibacterial substances, susceptibility to 



in relation to Gram's stain, 38, 170 

 Antibiotic agents, 155, 175 

 Antibodies. See also under Antigen-antibody 

 reactions 

 availability in tissues of host, 1058 

 blocking, in allergic reactions, 1159 

 distribution of in tissues, 1058 

 electrophoretic fractionation, 242, 246, 



248, 1030, 1092, 1385 

 fate of, after injection, 1124 

 formation of, 1101 et seq. 



adjuvants, effect of on, 1115 

 agglutinins O, formation of after 

 administration of antigen by 

 mouth, 1117 

 anamnestic reaction in, 1122 

 as evidence of specific infection, 1002 

 avitaminosis, effect of on, 1192, 1198, 



1204 

 blockade, effect of on, 1103 

 by synthesis in contact with antigens, 



1127, 1128 

 different antigens, in response to, 



1108 

 dispersal of inoculum, effect of on, 



1115 

 dosage, effect of on, 1107 

 in skin, 1102 

 in lymphocytes, 1105 

 in tissue cultures, 1105 

 in various organs, 1102, 1104 

 in vitro, 1128 

 local, 1101 

 mechanism of, 1127 

 metallic salts, effect of on, 1115, 1122 

 multiple antigens, in response to, 



1109 

 negative phase in, 1116 

 non-specific stimulus in relation to, 



1120 

 oral administration of antigen in 



response to, 1117 

 physiological fate of, 1127 

 pneumococcal polysaccharides, in re- 

 sponse to, 1684 

 primary stimulus in response to, 1106 

 protective action of in vivo, con- 

 ditions of, 1057 

 repeated injections, effect of on, 1113 

 reticulo-enclothelial system, role of in, 



1102 

 secondary stimulus in response to, 



1110 

 spleen, role of in, 1103 

 sulphonamides, effect of on, 1213 

 synthesis in vitro of, 1128 

 transference of via colostrum, 1077, 

 1088 

 via placenta, 1077, 1088 

 various factors, effect of on, 1104 

 various tissues, role of in, 1105 

 virus injections in, 1241 

 volume of inoculum, effect of on, 1114 

 general properties of, 194, 242 

 " heavy," 245 

 hcterophile. See Forssman antibody 



