INDEX— VOLUME II STARTS ON PAGE 971 



Antigen-antibody reactions, specificity of, 

 252 

 terminology employed in relation to, 194 



et seq. 

 toxin-antitoxin reaction, 238-240 

 antitoxin, unit of, 238 

 Danysz phenomenon in, 216, 240 

 Ehrlich's phenomenon in, 239 

 epitoxoids in relation to, 239 



toxin. Lq and L+ doses of, 239 



Minimal Lethal Dose of, 238 

 unit of antitoxin, 238 

 " two-stage " hypothesis of, 208 

 unitarian hypothesis of, 248 

 unity or diversity of antibodies, 248, 252 

 Antigenic structure of bacteria, 273-285. See 

 also under individual species 

 bacterial variation in relation to, 276 

 bacteriophage activity in relation to, 338 

 chemical methods in determination of, 



279 

 classification in relation to, 314 

 determination of by selective absorption 

 of agglutinins, 273 

 ' different antigen-antibody reactions in 

 relation to, 285 

 fallacies in determination of, 274, 275, 281 

 flagellar antigens, 276, 283, 284 



group and specific phases of, 279 

 Forssman antigen in, 282, 1090 

 H antigens, group and specific phases of, 



278 

 heterophile antigen in, 282 

 localization of antigens in bacterial cell, 



283 

 antigens, 277 

 optimal proportions, in determination of, 



276 

 roughness iir relation to, 277, 285 

 sharing of antigens by different bacteria, 



282 

 smoothness in relation to, 277, 285 

 somatic antigens, 276, 283 

 Antigenicity, of denatured protein, 261 

 of gelatin, 260 

 of proteins, 259 



role of carbohydrate in, 261 

 Antigens. See also Antigenic structure of 

 bacteria and Antigen -anti body reactions 

 atopens, relation of to, 1154 et seq. 

 bacterial. See under Antigenic structure 

 of bacteria 

 aggressins, relation of to, 1071 

 bacteriophage, in relation to, 338 

 endotoxins, relation of to, 1008 

 relation of to active immunization, 

 1055 

 basis of antigenicity of, 259 

 basis of specificity of, 252 

 chemical nature of in relation to stimu- 

 lation of antibody production, 1119 

 different, effect of simultaneous injection 



of, 1109 

 filtrable viruses, of, 1240 

 Forssman, 1089 



in bacteria, 282, 1090 

 general properties of, 194 



Antigens, haptens, 258 



aggressive action of in pneumonia, 



1071, 1679 

 anaphylaxis, role of in, 1141 

 antibody formation, stimulation of, 



by, 1119, 1684 

 bacterial polysaccharides as, 258 

 complex, 258 

 in filtrable viruses, 1237 

 in Forssman antigens, 1090 

 in human group A substance, 1090 

 inhibition of precipitation by, 257 

 relation of to complete antigens, 258 

 simple, 258 

 masked, 262 



nature and properties of, 252 

 organ specific, 252 

 persistence in body, effect on immunity of, 



1129 

 possible inclusion of in antibodies, 1127 

 proteins in relation to full antigenicity of, 



260, 1119 

 species, specific, 252 

 synthetic, 253-256 



diazo reaction in preparation of, 253 

 inducing type-specific immunity 

 against pneumococci, 1054 

 valency of, 262 

 vai'ious, names of, 195 

 Antipneumococcal immunity, experimental, 



in rabbit, 1037, 1048-1052 

 Antisepsis, Lister's studies on, 11 

 Antitoxic immunity, 1029-1033. See Im- 

 munity, antitoxic 

 Antitoxin. See also under iridividual diseases 

 avidity of, 1030 

 natural, 1075 el seq. See Antibodies, 



natural 

 route of administration of, effect of, 1124, 



1763 

 unit of, 238 

 Antiviral antibodies, 1237 

 Antiviral immunity. See Immunity, antiviral 

 Appendicitis, 149?" 



bacteriology of, 1497 

 isolation of Fusiformis from, 477 et seq. 

 Arrhenius and Madsen's theory of antigen- 

 antibody reactions, 199, 239 

 Arsenic compounds in chemotherapy, 155, 156, 



171 

 Arsenic-fast strains of spirochaetes in I'elapsing 



fever, 1808 

 Arthritis in rheumatism, 1509 et seq. 

 in joint ill, 676, 1284, 1496 

 infective of mice, 386, 1278 

 purulent, 1496 

 Arthus' phenomenon, 1151 

 Ascococcus mesenterioides, 627 

 Ascoli's thermoprecipitin reaction, 1738 

 Asjiergilli, 175 

 Aspergillic acid, 177 

 Asterococcus canis, 946 



mycoides, 940 

 Asthma, hypersensitiveness in relation to, 1153 

 Atopens, 1154 e< •seg'. 



simple compounds as, 1155 

 Aujesky's disease, 1941 



