VOL. 4 {1950) 



FUNCTIONAL ORGANIZATION OF THE BRAIN 



121 



Supporting data for such a sequence of changes during hypoglycemia^^ or acute 

 anoxia^'* is afforded by electroencephalographic tracings which reveal that the cortical 

 rhythm vanishes before the subcortical. Conversely the administration of glucose or 

 oxygen restores the subcortical waves before those of the cortex, additional evidence 

 that the cerebral cortex workes at a higher rate of activity and has greater demands for 

 energy than the subcortex. 



Turning to the problem of pentothal anesthesia, we find that pentothal, like the 



stage 



m 



Planel 



PlaneH 



PlaneM 



IF 



Clouding 



Hyper 

 sensitivity 



Light surgical 



Moderate 

 surgical 



Deep surgical 



Impending 

 failure 



Characterislics 



Euphoria loss 



of 

 discrimination 



impairment of 



environmental 



contact 



Loss of 

 consciousness 



Hypoactivity to 

 painful stimulus 



Loss of somatic 

 response to pain 



Loss of visceral 

 response to pain 



Fall in 

 pulse pressure 



Site of 

 depression 



Slight 

 depression 

 of cortex 



moderate 

 depression 

 of cortex 



Predominant 

 control by 

 subcortex 



Moderate 



depression 



of subcortex 



Predominant 

 control by 

 midbrain 



Moderate 



depression 



of midbrain 



Moderate 

 depression 

 of pons 



Brain 



Fig. 2. A correlation between the stages of pentothal anesthesia and the outstanding clinical signs 



and their neuro-anatomic allocations 



References p. 125. 



