VOL. 4 (1950) 



ACETALDEHYDE IN NORMAL METABOLISM 

 TABLE I 



333 



Acetaldehyde in mg 100 ml blood in rabbits treated with Antabuse (tetraethylthiuramdisulphide) 

 and in normal rabbits 



TABLE II 



Acetaldehyde formation per minute in isolated organs from rabbits treated with Antabuse and from 

 normal rabbits 



formation is negative. This indicates that the concentration of acetaldehyde is lower 

 in the blood which has been perfused through the organ than in the blood which enters 

 the organ. Of course the analytical error is rather high when determining small concen- 

 trations of acetaldehyde and so will influence the results considerably. Furthermore 

 substances other than acetaldehyde may give reactions which influence the determina- 

 tions to a considerable degree when small concentrations of acetaldehyde are found in 

 the blood. Nevertheless the production of acetaldehyde under the above mentioned 

 conditions appears to be of very little importance. 

 References p. 334. 



