CONTENTS 



VI. The (Estrus-Producing Hormone 



(a) History of preparation 

 {b) Chemical properties 



(c) Administration 



(d) Test-objects 



(e) Standardization 

 (/) Distribution 

 (g) Site of origin 

 (h) Pharmacological properties 



Vn. The Function of ffisTRiN 



{a) Action on test animals 



{b) Action on normal animals . 



(c) Limits of action 



{d) Attainment of puberty 



(e) QEstrin and the changes of the post-ovulation 



phase 

 (/) Significance of distribution 



Vin. The Periodicity of CEstrus 



{a) Role of the cyclic structures of the ovary 



(b) Relation between the Graafian follicle and the 



production of oestrus .... 



(c) Occurrence of oestrus after follicular ablation 



(d) Occurrence of follicular maturation without 



oestrus . 



(e) Reasons for supposing ovarian regulation to be 



external 



83 

 83 

 88 



91 

 93 



lOI 



106 

 113 

 113 



115 

 115 

 115 

 121 

 123 



125 

 131 



134 

 134 



134 



137 



148 

 149 



IX. The Relation between the Ovary and the 



Anterior Pituitary Body .... 152 



(a) Introduction ....... 152 



(b) Luteinization of the Graafian follicle . . . 153 



(c) The production of ovulation .... 158 



