0\^\RY AND THE ANTERIOR PITUITARY BODY 157 



however, was not confirmed (500). Injection of the sterilized 

 mouse possessing no Graafian folhcles results in the luteiniza- 

 tion of the whole of the first post-irradiation proliferation (see 

 p. 140J, and in the consequent inhibition of oestrus in the 

 accessory organs. This histological alteration of the ovary was 



Fig. 30. — Ovary of Rabbit injected with Sodium Hydroxide 



EXTRACT of ANTERIOR PiTUITARY, SHOWING LARGE NUMBERS OF 



ATRETIC Corpora Lutea. 



not permanent, however, and the cessation of injection w^as 

 followed by the reversion of the luteinized X-rayed ovary to the 

 normal X-rayed type and by the recurrence of oestrus. 



The action of these pituitary extracts has also been investi- 

 gated in the rabbit. In this animal, also, atretic corpora lutea 

 are produced on a large scale, but in many cases blood follicles 

 are formed (502). Many of the atretic corpora lutea are incom- 

 pletely solidified and contain a fluid centre consisting of blood 

 and liquor folliculi. In spite of these slight differences in histo- 



