158 INTERNAL SECRETIONS OF THE OVARY 



logical effect, the usual characteristic luteal activity is found in 

 the ovaries of injected rabbits. 



In the immature animal sim.ilar luteinization of the follicles 

 occurs, neither ovulation nor oestrous changes in the accessory 

 organs taking place. Brouha (88) found that the action of 

 oestrin in the immature anima] is not materiall}^ inhibited by 

 such luteinization. 





T , .-*vM:t^v.-?^"\. ^ t .•■'.'''_, ^. ,- . /^ ■ 



1~ '■^K. 



¥\G. 57. — Luteal Tissue of Ovary of Fig. 56, showing 



HEALTHY CONDITION. 



(c) THE PRODUCTION OF OVULATION 



The amount of evidence suggesting that the ovary does not 

 regulate its own periodicity led Zondek and Aschheim in 1927 

 (656) to carry out most thorough researches on the effects of 

 other endocrine organs and body tissues upon the female 

 reproductive organs. As a result of these researches they came 

 to the following conclusions: 



(a) Implantation of male or female anterior pituitary into the 

 immature mouse brings about precocious oestrus, 

 including the ovarian changes. 



