i6o INTERNAL SECRETIONS OF THE OVARY 



plants, like the NaOH extracts, have no effect whatever on the 

 accessory organs in the ovariectomized animal. Smith and 

 Engle (581) found that the immature ovary after implant- 



^■■■ 



c"*-^. 



""V 



/ 



^Wtii'H 



f.- 



(«) 



(6) 



Fig. 59. — Effect of anterior pituitary Implants on Ovary 

 OF immature Rat. 



(a) control litter mate; (6) follicular maturation induced on 

 twenty-ninth day by eight daily implants of two mouse hypophyses 

 (From Smith and Engle). 



ation of anterior pituitary might be ten times as large as the 

 control in the rat or nineteen times in the mouse. This was 

 not due to any increase in size of mature follicles as compared 

 with the normal adult, but to a great increase in their number 

 and in that of the corpora lutea produced by ovulation. 



