INDEX OF SUBJECTS 



241 



of vaginal test, 96, 97 ; effect on im- 

 mature animal, 97 ; effect on uterine 

 contractions, 97 ; standardization of, 

 101-106 ; unit of, 102 ; weight of 

 unit, 104, 105 ; distribution of, 106- 

 112 ; specificity of, 108 ; occurrence 

 of, in male, 109 ; yields of, 11 1 ; site 

 of origin, 113 ; pharmacological pro- 

 perties, 113, 114; effect on growth 

 and activity, 114; effect on test 

 animals, 115 ; effect during im- 

 maturity, 116, 124 ; effect during 

 anoestrus, 117 ; effect during dioes- 

 trus, 117 ; effect during pregnancy, 

 118; effect during lactation, 119; 

 effect on follicular maturation, 119 ; 

 clinical results with, 120 ; action on 

 male, 121 ; action on birds, 121 ; 

 limits of action, 1 21-123 ; ^^d copu- 

 lation, 125 ; relation to post-ovula- 

 tion changes, 1 25-131 ; effect on 

 vagina, 126 ; effect on uterus, 126 ; 

 relation to menstruation, 128 ; effect 

 on mammary gland, 129 ; signifi- 

 cance of distribution, 131-133 ; pres- 

 ence in liquor folliculi, 135 ; action 

 of during lactation, 183 ; effect on 

 sensitivity of uterus to oxytocin, 205. 



Oestrous cycle, essential features of, 23; 

 types of , 25, Chap. I\'. ; comparative 

 changes during, 27 ; in Dasyuriis, 28; 

 in opossum, 29 ; in dog, 31 ; in 

 guinea-pig, 34 ; during lactation, 39, 

 43, 44, 54 ; in horse, 40 ; in sheep, 

 40 ; in pig, 41 ; in mouse, 43 ; in 

 rat, 43 ; in rabbit, 54 ; in ferret, 60 ; 

 nature of, in various mammals, 68 ; 

 mammary changes during, 130 ; 

 length after X-irradiation, 144 ; re- 

 gulation of, 146-148 ; effect of 

 thallium feeding, 148 ; length after 

 unilateral ovariectomy, 150. 



Oestrus, 22 ; criteria of, 94 ; relation 

 of Graafian follicle to, 134 ; relation 

 to corpus luteum, 134; precocious, 

 158 ; periodicity of. Chap. VIII. ; 

 inhibition of, 176 ; relation to par- 

 turition, 200. {See also Oestrin.) 



Oestrus-inhibiting hormone, prepara- 

 tion of, 179, 180 ; distribution of, 

 181 ; properties of, 181 ; assay of, 

 181. {See also Corpus luteum.) 



Oestrus-producing hormone, see Oestrin. 



Opossum, theca interna in, 5 ; oestrous 

 cycle in, 29 ; period of gestation, 68 ; 

 mammary gland, 130 ; source of 

 oestrin in, 136. 



Ornithorhynchus, theca interna in, 5 ; 

 corpus luteum in, 9 ; development of 

 mammary glands of, 193. 



Ovarian capsule, 13. 



Ovarian cycle, in Dasyurus, 28 ; in 

 opossum, 30 ; in dog, 31 ; in guinea- 

 pig. 35 ; in cow, 37 ; in horse, 40 ; 

 in pig, 41 ; in mouse and rat, 45 ; 

 in rabbit, =f^ ; in man, 63 ; corre- 

 lation with parturition, 200 ; effect 

 on oxytocin production, 204. 



Ovarian extracts, early work on, 80, 83. 



Ovarian graft, histology of, 76 ; effects 

 of, 78; toanimalsof different age, 149. 



Ovariectomy, effects of, 70 ; in birds, 

 70 ; effects on secondary sexual 

 characters, 72 ; effects on ductless 

 glands, 72 ; effects on accessory 

 organs, 73, 74 ; pregnancy after, 98 ; 

 effect during pregnancy, 196, 206. 



Ovary, structure of, 4 ; accessory, 12 ; 

 regeneration of, 98 ; weight of unit 

 of oestrin from, 105 ; yield of oestrin 

 from, III ; grafts of, 149 ; hyper- 

 trophy of, 150 ; hypotrophy of, 130 ; 

 relation with other endocrine organs, 

 152 ; effects of anterior pituitary ex- 

 tracts on, 153-164 ; influence on 

 anterior pituitary body, 172. {See 

 also Ovarian cycle.) 



Ovulation, changes preceding, in fol- 

 licle, 6 ; time of, in Primates, 65 ; 

 time of, in bat, 135 ; production of 

 by anterior pituitary extracts, 158^ 

 inhibition of by corpus luteum, 175. 

 {See also Ovarian cycle.) 



Ovum, structure of, 6 ; multinucleate, 

 7 ; effect of X-rays on, 139. 



Oxytocin, role in parturition, 203 ; 

 effect of ovary on production of, 204 ; 

 changes in uterine sensitivity to, 205. 



Papio, \-ulval cycle in, 65. 



Para-lutein cells of corpus luteum, 9. 



Parturition, Chap. XI. correlation with 

 ovarian cycle, 200 ; relation to oes- 

 trus, 200 ; inhibition of, 201 ; role 

 of oxytocin, 203 ; relation to effects 

 of ovariectomy, 206. 



Pig, theca interna in, 5 ; corpus luteum 

 of, 9 ; breeding season in, 23 ; oes- 

 trous cycle in, 41 ; age of puberty in, 

 68 ; size of litter in, 68 ; period of 

 gestation, 68. 



Pineal gland, 72. 



Pituitary body, after ovariectomy, 72. 

 {See anterior pituitary body, and 

 oxytocin.) 



Placenta, extracts of, 84 ; weight of 

 unit of oestrin from, 105 ; yields of 

 oestrin from, 112 ; presence of oes- 

 trin in, 132 ; anterior pituitary 

 hormone in, 167. 



