Cumulative Subject Index 



33 



17-Hydroxycorticosteroids, effect on water 



and electrolytes, 4, 79 

 1 7-Hydrox>T)rogesterone, 1, 127, 128 

 Hydroxyproline, in skin elastic tissue, 1, 



88 

 Hypercapnia, renal effects of, 4, 265-266 

 Hypercholesterolaemia, 3, 136 

 Hypernatraemia, and cerebral disturb- 

 ances, 4, 36-44 



due to diarrhoea, 4, 58 



due to water deficiency, 4, 38-44 

 Hypertension, renal aspects of, 4, 258 

 Hypertonic saline, effect on hyponatrae- 



mia, 4, 50 

 Hyponatraemia, 4, 44-55, 95 



and cerebral disturbances, 4, 36-37 



and steroid output, 4, 60 

 Hypophysectomy, effect on foetus, 2, 166 



effect on ovary, 2, 60-65 

 Hypothalamus, effect on thirst, 4, 37 

 Hypothermia, in hamsters, 1, 168; 2, 248 

 Hypoxia, effect on diuresis, 4, 8 



Ide, lifespan of, 5, 223 

 Inbred strains, 3, 6-8 



and parabiosis, 3, 116, 124, 127-129, 

 130 



carcinoma in, 3, 117, 118-119, 120, 121 



cause of death in, 3, 120, 121 



development of, 3, 115-119, 127 



in experimental gerontology, 3, 115- 

 130 



lifespan of, 3, 13, 119-120, 121 



ovarian function in, 3, 119-120, 126, 

 127 



survival of, 3,13 



transplantation in, 3, 1 16, 120, 122-123, 

 126, 129 

 Index of cephalization, 5, 123, 135 

 Industrial performance, studies in, 3, 151, 



153, 164-167 

 Infants, electrolyte metabohsm in, 4, 78- 

 79, 154-164 



water metabolism in, 4, 78-79, 154-164 



water retention in, 4, 96-98 

 Lifection, resistance to, as measure of 



ageing, 1, 6 

 Infectious disease, in fish, 5, 213-214 

 Insects (see also under names of species) 



ageing in, 5, 247-268 



in nutritional research, 1, 174, 175 



lifespan of, 5, 105 



overwintering in, 5, 232-234, 240 

 Insemination, artificial, 1, 171 

 Insulin, effect on placenta, 2, 141 

 Insulin sensitivity, 1, 237 

 Intellectual behaviour, 3, 175-177, 182 

 Intelligence, changes in with age, 1, 36-39 ; 



3, 170-187 

 Interstitial cells, in testis, 2, 91-96 

 Involutional melancholia, 1, 44-45 

 Involutional psychosis, 3, 134 

 Iodide, diffusion of through aortic tissue, 



1, 72-74 



12 



Iron, content of apocrine sweat glands, 2, 

 191-193, 195 



in heart muscle, 3, 111, 112 



metabolism of, 3, 109-110, 112 

 Irradiation, effect on lifespan, 5, 19-20, 

 138-141,282,290,292 



effect on onset of disease, 5, 87, 88 



effect on ovary, 3, 127 



effect on thyroid, 3, 55 

 Isoleucine, in elastin, 1, 91, 94, 96 



Jack, lifespan of, 5, 220 

 Jacob-Creutzfeldt's disease, 3, 134 



Kwashiorkor, 1, 190-191 

 Kar> oplasm, 2, 90, 91 

 Keratinization, in gums, 3, 72 

 Ketosteroids, in testis, 2, 98, 99 



in urine, relationship with adrenal 

 steroids, 1, 128-130, 133-139 

 17-Ketosteroids, changes in excretion due 

 to age, 4, 91 

 daily excretion of, 1, 131-133 

 excretion of, age changes in, 1, 126-140 

 in elderly and schizophrenics, 1, 221- 



222, 223-236 

 in elderly subjects treated with 

 steroids, 1, 134-136 

 Kidney, age changes in, 4, 234-235 

 amyloidosis in, 3, 122, 125, 126 

 blood content of, 3, 52, 58 

 blood flow in, 3, 191-192; 4, 248 



age changes in, 3, 88 

 changes in due to age, 4, 227-228, 229- 



249, 253-254 

 concentrating ability of, changes in due 



to age, 4, 11-12,243-244 

 diseases of, effects of age, 4, 250-263 

 effect of Dibenamine, 4, 281, 282 

 effect of obesity, 4, 254, 255, 260 

 effects of potassium deficiency on, 4, 



262-263 

 effects of pyrogen, 4, 235-238 

 effect of water deficiency of, 4, 43 

 en2ymes in, 4, 245 

 function, 4, 229 



in respiratory failure, 4, 264-270 

 variations with age, 1, 220 

 glomerular filtration rate, changes due 

 toage, 4, 231,248 

 in congestive heart failure, 4, 275, 

 277 

 growthof, 4, 251-252 

 hormonal damage to, 4, 256-258, 262 

 in congestive heart failure, 4, 272, 273, 



276, 282, 283, 284, 287 

 in cor pulmonale, 4, 266-267 

 lesions of, causing loss of water, 4, 39 

 overloading producing senile changes, 



4, 254-255, 260 

 plasma flow in, changes in due to age, 

 4, 229-231, 235 

 effect of pyrogen, 4, 237-238 

 regeneration of, 4, 252-253 



