W19] Vi \l;Y MEDICINE. 385 



■• The blood of b sheep which has recovered from the disease produ led by Inocu- 

 lation does aol continue to be Infective by Inoculation to others as In the i 

 oi piroplasmosis (red water), and it is therefore unlikely thai ticks can Infect 

 themselves from such animals. The same is true of material taken from ;i 

 chronic case of Louping-ill contracted by natural Infection. 



•■ \ sheep which has passed through e reaction following upon Inoculation 

 is protected t" a very considerable extenl against the effects of a subsequenl 

 Inoculation, just as a sheep recovered from louping-ill In the field la highly 

 resistant to further attacks. A small cumber of sheep which had been Inocu- 

 lated at the laboratory with Mood survived exposure In the following season 

 on louping-iU Infected pasture, while l out of 12 other sheep ool bo Inoculated 

 ami exposed on the same pasture died of typical louping-ill. The blood of 

 healthy sheep when Inoculated in large amount to other sheep does act cause 

 a reaction, 



"The disease which has been produced experimentally by larval ticks </. 

 ri(iinis) from females off sheep affected with Louping-iU and by adults which 

 had fed as nymphs on Infected sheep, and by the Inoculation of gland Juice and 

 hlood from such sheep, is, in fact, louping-ill. To conclude otherwise would 

 involve the following further conclusions which are very difficult of acceptance: 

 (a) That the experimentally produced cases with conclusive symptoms and 

 lesions described in part l, . . . must be disregarded; (b) that there is a 

 disease of sheep other than louping-ill, characterized by similar microscopic 

 lesions and by similar varying symptoms which is tick-borne and InoCUlable, 



and that sheep Suffering If acute and typical louping-ill in the held are 



invariably attacked at the same time by this other disease, since Inoculation 

 of their gland juice or blood constantly produces it." 



The transfusion of tuberculous sheep with the blood of normal and im- 

 munized sheep, including a study of sheep tuberculosis controlled by the 

 complement fixation test. E. Mates and I >. J. Ilii:'i:v (Auur. Rev. Tubercu- 

 losis, 2 (1918), No. I". pp. 604-614). — Transfusion of tuberculous sheep with 

 normal and with immune blood was conducted for tiie purpose of determining 

 the value of blood transfusion in the treatment of tuberculosis. In both <•; 

 the animals outlived the control, although tho condition of the animal receiv- 

 ing the immune blood was much better than that of the one receiving normal 

 blood. 



The authors are of the opinion that, while the results are in no way con- 

 clusive, normal blood on repeated transfusion is of slight value, while blood 

 containing antibodies is possibly of considerable value in the treatment of 

 tuberculosis. 



Immunization against swine erysipelas in 1917. F. IUkki {Schweiz. Arch. 

 TierheUk., 60 (1918), No. 6. pp. 878-875).— In the practice of the author, suc- 

 cessful immunization against erysipelas consists of in simultaneous Im- 

 munization of healthy stock, (2) therapeutic Inoculation of stock sick with 

 urticaria (diamond-skin disease), whereby si-k ami apparently healthy swine 

 receive the same amount of serum, and (3) therapeutic inoculation of stock 

 affected with the acute form of the disease, followed by simultaneous im- 

 munization. 



The effect of " ground glass " on the gastrointestinal tract of dog's, .7. S. 

 Simmons and YV. < J. von <Ji aiin (Jour. Amer. M< '. iMOC., 71 i t918), Vo. US, pp. 

 2127. 2128). — "The Ingestion of ground or powdered glass has no toxic effect 

 and produces no lesion, either gross or microscopic, on the gastrointestinal 

 tract of dogs." 



