380 EXPERIMENT STATION RECORD. [Vol.40 



the work of the years 1916 and 1917 with infectious diseases of live stock. 

 Particular attention was given to the work of eradication of bovine tuberculosis 

 in cooperation with the U. S. Department of Agriculture. 



Annual report of the State veterinarian of Nebraska for the year 1918, 

 J. S. Anderson (Arm. Bpt. State Vet. Kebr.. 1918, pp. 163). — This report in- 

 cludes an account of the occurrence of and work with infectious diseases of 

 live stock during the year. 



Report of the civil veterinary department. Assam, for the year 1917-1S, 

 YV. Harris (Rpt. Cir. Vet. Dept. Assam, 1911-18, pp. 2+14+2).— The usual 

 annual report (B. S. R., 38, p. 180.) 



Eradication of disease from the farm, H. J. Washburn (Hoard's Dairyman, 

 1918. Dec. 27, pp. 778, 773. 778, 779, figs. 5). 



Specific fats as factors in immune processes, C. C. Wabdkr [Jour. Infect. 

 Diseases, S3 (1918), No. 6, pp. 50J f -52l). — This is a continuation of work pre- 

 viously noted (B. S. EL, 39, p. 80). 



Experimental evidence is given that the fat complexes characteristic of 

 certain bacteria and other cells, obtained either from the cells or assembled 

 artificially, arc capable of replacing the cells themselves in the production of 

 specific antibodies In the blood of rabbits Injected with them. The relation of 

 fats to antibody causation is discussed in detail. 



The author considers thai the specificity of the antibodies obtained by the 

 injection of cells probably depends in part or wholly on the configuration of 

 the fats constituting the hulk of the cell surfaces. 



The coagulation of the blood and anaphylactic shock. H. A. BULGES (Jour. 

 Infect. Diseases, S3 (1918), No. 6, pp. •" I). — The relation of anaphylaxis 



to the coagulation of the blood was studied by means of determining the effecl 

 of anaphylactic shock on coagulation time, and the prothrombin and antithrom- 

 bin factors of coagulation of the blood of cats, rabbits, dogs, and guinea pigs. 

 The following conclusions were drawn: 



"The changes In the coagulability of the blood during anaphylactic shock are 

 due to changes In that stage of the coagulation process at which thrombin is 

 formed through the Interaction of prothrombin, calcium, thromboplastin, and 

 antithrombin (?), These changes are probably due to variations in thrombo- 

 plastin. Antithrombin changes are nol great In some animals there may be an 

 Increase in antithrombin, which would aid in retarding the coagulation of the 

 blood. There is no Increase in antithrombin in rabbits. There was a marked 

 increase in the rale of fibrinolysis after anaphylactic and peptone shock." 



On the mode of action in vitro and the preparation of hemolytic anti- 

 bodies, A. K. Balls and J. II. KoBNS (Jour. Immunol.. 8 (1918), No. •">. pp. 

 375-887). — The work reported was undertaken to study the mechanism of 

 amboceptor action in vitro and to ascertain if possible what part of the red 

 hi 1 ceils is responsible for their antigenic property. The results are sum- 

 marized as follows : 



"In vitro, as hemolysis proceeds, the total amount of amboceptor is constant, 

 but the Btrome of the laked red cells increasing in amount become less and less 



saturated with ami eptor, and so split off less of it by dissociation, thus 



causing the velocity of hemolysis to decrease. In vivo the stroma produce 

 specific hemolytic and agglutinative bodies of high titer. Since little protein is 

 injected, the toxicity seems to be nil. 



"Alcohol and ether extracts, as well as 0.85 and 5 per cent salt solution ex- 

 tracts, of the stroma do not hind amboceptor in vitro. The extract of stroma 

 with alkaline physiological salt solution does bind amboceptor in vitro, and on 

 Injection causes the development ><f specific hemolysins bu1 nol of agglutinins. 

 This alkaline extract contains nucleo-protein, but not simple albumin or glo- 



