284 EXPERIMENT STATION RECORD. [Vol to 



Bacteria of infectious diseases of man and animals, D. H. Jones (Ontario 

 Dept. Agr. Bui. 265 (1918), pp. 38-68, figs. 7). — A popular summary of infor- 

 mation. 



[Report of] health of animals branch, T. A. Ceerar (Rpt. Mitt. Agr. Canada, 

 1018, pp. 58-65). — A brief summary of the occurrence of and work with the 

 more important diseases of live stock during the year under report. 



Annual administration report of the civil veterinary department in Balu- 

 chistan for the official year 1917-18, S. G. Haji (Aim. Admin. Rpt. Civ. Vet. 

 Dept. Baluchistan, 1917-18, pp. 13).— This, the usual annual report (E. S. It., 

 37, p. 274), includes an account of the occurrence of and work with infectious 

 diseases of live stock. 



Annual report of the civil veterinary department, United Provinces, for 

 the year ended March 31, 1918, K. W. Olives (Ann. Rpt. Civ. Vet. Dept. 

 United Pro'-.. 1918, pp. [6] +23). —This is the usual annual report (E. S. R., 38, 

 p. ISO). 



New and nonofficial remedies, 1918 (Chicago: Amcr. ifed. Assoc., 1918, pp. 

 452 + XXV I). —This is the 1918 edition of the book previously noted (E. S. R., 

 37, p. 87G). Certain products described in the 1917 edition have been omitted, 

 new products have been added, and some revisions have been made in the 

 definitions and statements of the physical and chemical properties of certain 

 substances. Special attention is called to the discussion of foods for diabetics, 

 of hypochlorites and hypochlorite substitutes, and of pollen extract prepara- 

 tions. 



Revised supplement to new and nonofficial remedies, 1918 ([Chicago: 

 Amer. M><i. Assoc, 1919], pp. 19). — This is a supplement to the book noted 

 above. 



Relative irritant properties of the chlorin group of antiseptics. G. E. 

 Cullen and H. D. Taylob [Jour. Expt. Med., .?,-,• (191S), Xo. 6. pp. 681-499, pis. 

 3, figs. 2). — The relative Irritant action of Dakin's solution prepared in various 

 ways, of other hypochlorite solutions, and of the organic chlorin antiseptics, 

 chloramln T and dlchloromin T. have been studied by means of the effect pro- 

 duced by these reagents on the ears of rabbits. From the observations report< 1 

 the following conclusions are drawn: 



Dakin's hypochlorite solutions, of which the alkalinity is kept within the 

 range of from 100 to 1,000 times the alkalinity of water (pH of 9.3 to 10.2) 

 by means of buffer salts, have practically the same degree of irritant action 

 whatever method has been employed in preparing these solutions. Solutions 

 that have an alkalinity less than that indicated by the end-point of alcoholic 

 solution of phenolphthalein (pll of 8.5 to 8.8) or greater than that indicated 

 by the end-point to powdered phenolphthalein (pH of 10.2) are intensely irri- 

 tating. Solutions of hypochlorite from which most of the calcium has been 

 precipitated and calcium hypochlorite solutli a less Irritating than Dakin's 



solution. Two per cent chloramin T solution has no irritant action, and 5 

 per cent dichloramin T in chlorcosanc and chlorcosane alone are only slightly 

 irritating. 



Dakin's solution and Dakin's oil in the normal peritoneal cavity of the dog, . 

 E. G. Grey (Bui. Johns Hopkins Uosp.. 29 (1918), Xo. .112. pp. it t-t ?.?).— Both 

 the neutral solution of chlorinated soda (Dakin's solution) and dichloramin T 

 in chlorinated paraffin (Dakin's oil) when Injected into the normal peritoneal 

 cavity of a dog were found to lead to an Inflammatory reaction, the decree of 

 which was directly proportional to the amount of chlorin antiseptic used. The 

 author emphasizes the necessity of caution In the use of chlorin antiseptics in 

 Intra-abdominal infections and the importance, if they are used, of maintaining 

 n adequate drainage tract. 



