1019] » - VETERINARY MEDICINE. 285 



A stujly of pyotherapy in various suppurations, G. A. CHAinzi (RSc. Mid. 

 V6t., 94 (Wis), x<>. 15-n, pp. 403-411).—The author, In cooperation with 

 Dupont, has tested the efficacy of autopyotlicrapy and of monovalent and poly- 

 valent pyotherapy in the treatment of various anppnrating wounds. 



Excellent and similar results were obtained with all (he methods employed. 

 The general results are summarized, from which the conclusion is drawn that 

 pyotherapy should be considered as an adjuvant rather than a panacea and 

 should be used only in connection with the usual surgical treatment. Its mode 

 of action is considered to be a stimulation of phagocytosis augmenting the 

 natural defense of the organism rather than the creation of a state of resistance 

 conferring immunity. 



Sterilization of the skin and other surfaces by a mixture of crystal violet 

 and brilliant green, V. Bonney and C. H. Bbowning (Brit. Med. Jour., No. 

 299-i (1918), pp. 562, 563; abs. in Vet. Rev., 2 (1918), No. J,, pp. l,8.' h .',85).— The 

 solution employed contains 1 per cent of a mixture of equal parts of crystal 

 violet and brilliant green dissolved in equal parts of rectified spirit and water. 

 Tilt- skin of the operation area is painted with the solution six hours before the 

 operation, and is then covered with lint soaked in the solution and protected by 

 waterproof cloth. This is kept on until the operation. A sterile and actively 

 antiseptic condition of the skin with no irritation is produced. 



The results of the application of this method have been satisfactory both in 

 Chemical and in bacteriological tests. 



The protective action of diet against tartrate nephritis, W. Salant and 

 A. M. Swanson (Jour. Pharmacol, and Expt. Titer., 11 (1918), No. 1, pp. 4#- 

 62). — "When tartrate was given by mouth to rabbits on a diet of oats large 

 doses were required to inhibit the elimination of phenolsulphonephthalein. The 

 effects produced with medium doses were very moderate. Recovery was ob- 

 rerved in all cases. Even small doses of sodium tartrate injected subcutaneously 

 into rabbits on a diet of oats caused a very pronounced inhibition of the elimi- 

 nation of dye. Considerable improvement occurred after three to five days, but 

 complete recovery of function was never observed. 



" Evidence of disturbance of the renal function was seldom obtained with 

 medium doses of sodium tartrate when Injected subcutaneously into rabbits on 

 a diet of fresh young carrots. Large doses showed a decrease of functional 

 activity within a few hours after injection, but tests made one or more days 

 later indicated considerable improvement and in some cases recovery. 



"After the subcutaneous injection of sodium tartrate into rabbits on a diet 

 of oats, the time of appearance of the phenolsulphonephthalein injected was 

 delayed and the duration of elimination longer than in rabbits which had been 

 receiving carrots. 



" When sodium tartrate was injected subcutaneously in gradually Increasing 

 amounts, no impairment of renal function was observed even after very large 

 doses (4 and 6 gin. per kilogram) if the diet consisted of carrots exclusively, 

 but the efficiency of the kidney was markedly decreased if oats alone were fed, 

 although the amount of tartrate administered was only one-fourth or one-sixth 

 of that given to rabbits on a diet of carrots." 



The influence of diet on the toxicity of sodium tartrate, W. Salant and 

 A. M. Swanson (Jour. Pharmacol, and Expt. Ther., 11 (1918), No. 1, pp. 27- 

 lil). — "The toxicity of sodium tartrate was most marked on a diet of oats, hay, 

 and cabbage. Diets rich in sugar were efficacious in decreasing toxicity, the 

 effect being most pronounced on a diet of young carrots. A marked Increase 

 of resistance to tartrates was also observed on a diet of carrot leaves. 

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