1019] VBTERINABT MEDICINE. 583 



seldom that more than two <>r three doses are required, in severe cues In- 

 travenous Injection is considered preferable, it is snid thai the serum, If 

 heated twice to 66° • '., Beldom produces serum sickness. The author is of the 

 opinion that normal bovine serum may also !)<■ efficient In tin- treatment of 

 Other Infectious diseases, such as the plague, cerebrospinal meningitis, etc. 



Tartar emetic in the treatment of derrengadera, J. Iin;in: (Gac. .!/<</. 

 0ordo*8, 25 (1918), No. 6, pp. 62, 63; abs. in Vet. Jour.. 7-} (1918), No. 5/7. pp. 

 166, 967; Trap. Vet. Bui., 6 (1918), No. 3, pp. 154, 155).— In the treatment of 

 the trypanosomiasis known in Venezuela as derrengadera (mal-de-caderas), 

 1 to 1.5 gnx of emetic dissolved in 100 cc. of chlorid solution at 4:1.000 and 

 injected intravenously at intervals of 5 days resulted in the cure of all the 

 animals treated. 



Favus herpeticus or mouse favus. — Possibility of production of favus in 

 man from Australian wheat, R. E. Buchanan (■Jour. Amer. Med. Assoc, 7% 

 (1919), No. 2, pp. 97-100).— Thin is a report of studies by the Hygienic Labora- 

 tory id' the D. S. Public Health Service, made with a view to determining whether 

 or not there is danger that men engaged in this country in the handling and 

 milling of Australian wheat may become infected with the dermatophyte 

 [chorion quitiokeannm. The conclusions drawn from the studies are as 

 follows : 



"There exists in many parts of Europe and in Australia and probably in the 

 Doited Stales ami in other parts of the world a disease, mouse favus, the cause 

 of a highly fatal infection among mice and not infrequently transmitted to man, 

 producing a herpetiform favus of the smooth skin. The disease in man usually 

 yields readily to treatment. 



" Samples of mouse skins and of wheat from Australia failed to show evi- 

 dence of favus. That the disease is prevalent among the field mice that have 

 attacked the Australian wheat stores seems to be established through the ac- 

 counts of Paul and of Lawrence. It is not improbable that cases of favus 

 herpeticus may arise occasionally among men who handle the imported Aus- 

 tralian wheat or in animals, particularly rodents, that feed on the grain or on 

 certain of the mill by-products. 



"It is not probable that the danger from the disease is great enough, or 

 lie disease itself serious enough, to warrant interference with the Import a tion 

 of the wheat from Australia." 



Prompt macroscopic agglutination in the diagnosis of glanders, O. R. 

 Povitzky {Jour. Immunol, 3 (1918). No. 6, pp. 463-479).— A method is de 

 scribed by means of which it is stated that a prompt, clear cut macroscopic 

 agglutination for the diagnosis of glanders can be obtained in two hours. For 

 success in the reaction, it is necessary to use a strain of BaciUus mullet which 

 has proved to be constant and of native agglutinabllity, to prepare very care- 

 fully the medium in which It is grown, and to neutralize all the glassware used 

 in connection with the cultures. 



The medium which has given the most satisfactory results is potato-glycerin- 

 veal agar that is 2.5 per cent acid to phenolphthalein. Slants of this medium 

 are inoculated with 48-hour cultures of the organism. After 48 hours' incuba- 

 tion at 37° C, the growth is washed off with 0.85 per cent salt solution and 

 killed by heating at 60° for 2 hours. A little carbolic acid is added to this stock 

 suspension, which can be kept in the ice box for two months or more if handled 

 with aseptic precautions. 



The tests are carried out with a fresh dilution of the stock suspension made 

 by adding 0.8n per cent saline solution. A primary dilution of the serum 

 (1 : 40) is made, and used in varying quantities with 3 cc. of the bacterial sus- 



