880 EXPERIMENT STATION RECORD. [Vol.40 



The manufacture of Cheddar cheese, R. H. Leitch (Vest of Scot. Ayr. Col. 

 Bui. 88 (1918), pp. 81-100). — The British method of making Cheddar cheese is 

 outlined. 



VETERINARY MEDICINE. 



Report division of veterinary. W. Moore (Bui. .V. C. Dept. Agr.. 39 (1918), 

 No. 12, pp. 52-57). — This is a report for the biennial period December 1, 1916, 

 to December 1, 1918. on tick eradication work, hog cholera, tuberculosis, 

 glanders, etc. 



Researches on the serum of the sea eel (Muraena helena). W. Kopaczewski 

 {Ann. hist. Pasteur, Si (1918), No. 12, pp. 584 ''>'■■ ftff*- 10).— This is a more 

 detailed treatment of the subject previously noted (E. S. K.. 38, p. 582). 



Hematic phenomena in anaphylaxis and antianaphylaxis (hemo-anaphy- 

 lactic crisis), C. Richet, P. Brodin, and F. Satnt-Gibonb (Compt. Rend. Acid. 

 8ci. [Paris'], 168 (1919), No. 8, pp. S69S83, figs. .}).— Anaphylaxis experiments 

 with dogs are reported which indicate that in anaphylaxis the blood under- 

 goes profound changes, including an increase in concentration, the appearance 

 of nucleated hematin. and the disappearance of polynuclear colls. 



A blood-destroying substance in Ascaris lumbricoides, B. Schwartz (Jour. 

 Agr. Research [V. «.], 16 (1919), No. 9, pp. 253-258) —Thi* is a preliminary 

 report of Investigations conducted by an agenl of the Zoological Division of the 

 r. s. Department of Agriculture. The author's investigations arc said to have 

 resulted in the accumulation of sufficient data to warrant the following con- 

 clusions : 



"The body fluid of A. lumbricoides taken from worms shortly after their 

 removal from the host Is not hemolytic t<> the washed erythrocytes of swine, 

 cattle, sheep, rabbits, guinea pigs, and rats. The fluid from worms which after 

 removal from their host arc kept alive in salt solution for a few days acquires 

 hemolytic properties. Fluid from worms kept in vitro for 24 hours is only 

 slightly hemolytic if at all, hut fluid from worms kept under similar condi- 

 tions from six to eight days is decidedly destructive to the red blood corpuscles 

 of swine and sheep. The hemolytic property of the fluid is thermostabile and is 

 not destroyed by boiling. 



"There appears to be an inverse relation between the hemolytic property of 

 the fluid and the presence of Oxyhemoglobin in it. Fluid from fresh worms 

 contains oxyhemoglobin and is nonhemolytic. When, however, the worms are 

 kept alive in vitro, the oxyhemoglobin disappears from the fluid and can no 

 longer be detected by spectroscopic examination one week after the worms 

 have been removed from the host. Meanwhile, the fluid becomes hemolytic. 

 Whether oxyhemoglobin in itself is the sole factor In the Inhibition of hemolysis 

 or whether other substances are Involved which are associated with the oxy- 

 hemoglobin and disappear Simultaneously with it has not been determined. 



"Salt solution extracts of the worms made by grinding up 4 to 1<> ,u r m. of the 

 fresh body substance of the parasites and suspending it In 100 ee. of an 0.88 

 per cent solution of sodium chlorid are hemolytic to the washed erythrocytes of 

 swine and other mammals, the hemolytic potency of the extracts varying 

 directly within certain limits with the duration of the extraction. The reaction 

 Is independent of the acidity of the solution, since it is not Impaired by neu- 

 tralization. Extracts of dried worms in an 0.85 per cent solution of sodium 

 chlorid are decidedly hemolytic to the red corpuscles of various animals. 



" Salt solution extracts of the intestine of the worm are more destructive to 

 blood corpuscles than extracts of the body wall, of the reproductive organs, or 

 of the entire worm. The various salt solution extracts also do not lose their 



