VETERINARY MEDICINE. 687 



treated with tubeivuliu take on weight, this being clue to an increase in the water 

 content of the btKly and, further, to changes in the metabolism of the mineral 

 matter. Very positive von Pirquet reactions and rapid weight reaction forecast 

 a favorable prognosis. 



Bernaeck's tuberculin and its method of application, E. BfiBANECK {Edinb. 

 Med. Jour., u. ser., 3 (1909), No. 6, pp. 522-533; abs. in CentU. Bakt. [etc.], 1. 

 AM.. Rcf.. J,6 (1910), No. 13-JJ,. p. y/27).— This tuberculin contains an exo- and 

 an endo-toxin, and when injected acts similar to a vaccine. The tuberculin is 

 generally injected subcutaneously, but when possible, as for instance in surgical 

 cases, should be injected directly into the tubercular foci. 



The diagnostic value of tuberculin for tuberculous hens and turkeys, 

 Klimmer and Saalbeck (Ztschr. Ticnned., U, (1910), No. 3, pp. 222-239).— As 

 the result of 114 thermal tuberculin tests, 270 ophthalmic reactions, and 282 

 cutaneous reactions with various tuberculin preparations (tuberculinum hominis. 

 bovis and a\'is, bovotuberkulol, ttiberculinum siccum humanum and bovinum) 

 with tuberculous and nontubercular hens and turkeys infected with human and 

 bovine tubercle bacilli, the author concludes that the tuberculin preparations 

 mentioned can not be employed for diagnosticating tuberculosis in domestic 

 fowls. 



Further investigations in regard to immunity against tuberculosis, ■with 

 a contribution to phthisisogenesis, Romeb (Bcitr. Klinik Tubcrkulose, 13 

 (1909), No. 1, pp. 1-63; abs. in Ztschr. Tuberkulo.se, 16 (1910), No. 1, pp. 77, 

 78). — The treatment of guinea pigs with dead and living virulent tubercle 

 bacilli gave no immunity. With chronic tubercular guinea pigs, however, im- 

 munity against a second massive infection was practically produced, but the 

 stimulation of this second infection predisposed to cavity formation in the 

 lung. The same results were also obtained with sheep and bovines. 



Are tubercular animals immune toward their own tubercle bacilli? E. 

 JoEST (Ztschr. Infektionskrank. u. Hug. Haustiere, 6 (1909), No. 3-Ji, pp. 256- 

 26-'i). — A criticism of Romer's conclusions (see above) from the findings ob- 

 tained in the pig and bovine. The author concludes that the tissues of a tuber- 

 cular animal do not possess any increased immunity toward " tubercular meta- 

 static auto-infection (haunatogenous and lymphagenous varieties)." 



Experimental investigations about tuberculosis immunity, P. H. Romeb 

 (Ztschr. Infektionskrank. ii. Him. Haustiere, 6 (1909), No. 6, pp. 393-'f05).—A 

 polemical article (see above), giving the results of four experiments with sheep, 

 two of which were reinfected with markedly virulent tubercle bacilli after a 

 period of about 8 mouths. The other two animals were sound and from a 

 flock free from tuberculosis and were given an initial dose of the tubercle 

 bacilli. The results on autopsy showed that a certain degree of immunity 

 against a second infection is possessed by the reinoculated animals. 



Remarks in regard to Romer's experimental work in reference to tuber- 

 culosis immunity, E. .Joest (Ztschr. Infektionskrank. u. Hyg. Haustiere. 6 

 (1909), No. 0. pp. .'i06--'i0S). — 'The author liolds that Romer in his work (see 

 above) has furnish(>d proof in regard to an additional infection l)ut none for a 

 " metastatic auto-infection." 



Antituberculous vaccination in the ox, S. Abloing (Vet. Jour., 66 (1910), 

 No. J/20, pp. SI 5-325). — These vaccination tests were made with 60 bovines at 

 least 4 months old and not over a year, and with attenuated human and bovine 

 tubercle bacilli which were capable of being transmitted through successive 

 cultures, had good viability, and did not produce tuberculosis in the animal 

 when doses of from * to 1 cc. were given. The injections were made intra- 

 venously, subcutaneously, and per the digestive tract. 

 63100°— No. 7—10 7 



