84 EXPEEIMENT STATION EECOED, 



case of dextrose. It does uot appear to he deflnitely associated with the 

 amount of acid produced." 



On the production of precipitins, L. Hektoen (Jotir. Infect. Diseases, U 

 {WW, No. 3, pp. 403-410, fii/s. 5; ahs. in Jour. Amer. Med. Assoc, 62 {1914), 

 No. 25, p. 1991).— ''Bj giving rabbits intraperitoneal injections of increasing 

 quantities of serum or blood on three successive days a serviceable precipitat- 

 ing serum may be produced in about 15 days. The same quantity of antigen 

 injected at one time also appears to give good results. The curve of the pre- 

 cipitin in such cases is lilje the simple antibody curve following a single in- 

 jection of other antigens. The injection of whole blood may be more advan- 

 tageous in producing more precipitins for blood proteins in general than the 

 injection of serum only. The injection of washed human corpuscles gives rise 

 to precipitins for human serum." 



Further observations on the presence of antibodies for Micrococcus meli- 

 tensis in the milk of English cows, S. L. Cummins, C. J. Coppingek, and A. L. 

 Ukquhart {Jour. Boy. Army Med. Corps., 23 {1914), No. 1, pp. 36-41).— In a 

 series of seven cows examined for agglutinations two gave positive results and 

 one of these was found to agglutinate M. mcUtcnsis in dilutions varying from 

 1:250 and 1:1,000 at different times. The milk of this cow was also investi- 

 gated for opsonins and deviating substances, and it was found that " the milk, 

 whey, and blood serum of the cow behaved toward M. melitensis in a manner 

 comparable to the body fluids of animals suffering from, or immunized against, 

 this organism. Due allowances were made for differences in concentration of 

 ' antisubstauces ' and degrees of immunity." 



Can bacteria circulating in the blood be eliminated through the wall of 

 the intestine? H. Beitzke {Ztschr. Uyg. u. InfektionslcranJc, 78 {1914), No. 2, 

 pp. 228-242). — ^The experiments were conducted with rabbits, each animal 

 receiving in the ear vein six loopfuls of a 4- to 8-day-old Bacillus prodigiostis 

 culture grown on potato. About one hour after the injection the micro-organ- 

 isms were noted in the bile. At the same time and in some instances earlier B. 

 prodigiosus was found in other parts of the intestine, but was never noted in 

 the stomach. In most of the cases the organisms were found in the ileum and 

 cecum. Sections of organs, but more especially parts of the alimentary tract, 

 were examined microscopically and the bacilli were never noted alone but 

 always inclosed in cells, mostly in leucocytes and in the liver in Kupffer cells. 

 This supports the theory that leucocytes aid in the transportation of organisms 

 into the intestines. 



Foot-and-mouth disease, J. II. Mohler {JJ. S. Dcpt. Agr., Farmers' Bid. 666 

 {1915), pp. 16, figs. 7). — ^This is largely a revision of the Department's earlier 

 publications on the subject. 



Vaccination with Loffler's serum against foot-and-mouth disease, J. 

 Matsciike {Arch. Wiss. 11. Prakt. Tierlicilk., 40 {1914), No. 6, pp. 516-538; abs. 

 in Berlin. Tieriirztl. Wchnschr., 30 {1914), No. 42, p. 707).— The results indicate 

 that when the serum is used under the conditions specified, it will prevent an 

 outbreak of the disease. The protection conferred, however, is not permanent. 

 The protective value of the serum is not dependent upon the virulence of the 

 infecting agents and 2 cc. and more of the serum when given subcutaneously 

 will absolutely prevent the occurrence of the disease. 



Tetanus: Its prevention and treatment by means of antitetanic serum, A. 

 MacConkey {Vet. Jour., 10 {1914), No. 413, pp. 555-576).— An account of 

 tetanus jind its preventive and curative treatment by means of antiserum. 



Regarding tubercle bacilli in the circulating blood of bovines, especially 

 after injecting tuberculin, L. Brante {Ztschr. Infektionskrank. u. Uyg. Haus- 



