VETEEINAEY MEDICINE. 279 



the recognized vermifuges were effective in expelling the greater number of 

 the parasites, but nearly all the ' remedies' failed to expel all the worms. The 

 most effective vermifuges tried in the experiments were turpentine, iron sul- 

 phate, copper sulphate, santonin, tobacco, and areca nut. Copper sulphate was 

 found to be the most efficient in expelling the thorn-headed worm. Each exiieri- 

 mental animal was kept in a separate pen during the experiment and was 

 slaughtered to determine the efficiency of the vermifuge administered." 



Experiments on complement flxation — hog cholera. — The blood sera of swine 

 were found hemolytic for the red blood cells of one experimental horse, one 

 goat, and two cows, but not for a third cow (No. 3) which was a reactor to 

 tuberculin. " Hemolysis occurred whether the blood serum used was from nor- 

 mal hogs susceptible to cholera, hogs affected with acute cholera, or from hogs 

 hyperimmunized to cholera. 



"In the attempts to prepare an 'antigen,' extracts were made from the blood 

 of six pigs suffering from the acute hemorrhagic tyjie of cholera; six alcoholic 

 extracts and six extracts with normal saline solution were used. The alco- 

 holic extracts prevented hemolysis, but check experiments showed this to be 

 due to the alcohol and not to an ' antigenic content ' of the blood. The normal 

 saline extracts, from blood, also failed to show the presence of a deviating an- 

 tigen." 



Separate saline extracts made from the spleen of six virus pigs failed to pre- 

 vent hemolysis. Saline extract prepared from the spleen of virus pigs gave a 

 distinct deviation with the erythrocytes of cow No. 3 and with the blood serum 

 of a hog hyi:>erimmunized to both the filterable virus and B, suipcstifer. In 

 quantities of 0.01 to 0.02 cc. of the spleen extract negative results were obtained 

 from the sera from other immune hogs and from hogs suffering with acute 

 cholera. The positive deviation obtained with the serum of the hyperim- 

 munized hog might have been caused by the B. suipestifer antigen and not by 

 the filterable virus antigen. " Some further te.sts are to be made with the serum 

 from this hog and cultures of B. suipestifer. Extracts from kidneys of ' virus 

 pigs ' failed to show any ' deviating content.' " 



Studies from the Rockefeller Institute for Medical Research (Studies 

 Rockefeller Inst. Med. Research, 20 {1915), pp. 591, pis. 32, figs. 25).— Reprints 

 of papers on work done at the Rockefeller Institute or under grants therefrom. 

 The topics dealt with are pathology and bacteriology, physiology and pharma- 

 cology, chemistry, experimental biology, and contributions from the Hospital 

 of the Rockefeller Institute. 



Some diseases, whose etiolog'y is unknown, discussed in the light of the 

 vitamin theory, R. Reinhardt {Berlin. Tierdrztl. Wchnschr., 30 {191Jf), Nos. 

 31, pp. 645SJf7; 38, pp. 6.57-66i).— Amongst the diseases discussed are poly- 

 neuritis gallinarum, trembles in sheep, and paralysis of the vestibular nerve in 

 pigeons. See also a previous note by Funk (E. S. R., 32. p. 57S). 



Some important animal parasites affecting Ohio live stock, D. C. Mote 

 (Ohio Sta. Bui. 280 {191',), pp. 23-52, figs. 2/).— This introduction to the sub- 

 ject calls attention to some of the animal parasites prevalent in Ohio and con- 

 trol measures therefor. A bibliography of 17 titles relating to the subject is 

 included. 



A revised check list of the animal parasites of domesticated animals in 

 India, S. H. Gaiger (Jour. Compar. Path, and Then, 28 {1915), No. 1, pp. 67- 

 76). — ^A revision of a check list previously noted (E. S. R., 22, p. 791). 



Abderhalden's protective ferments, C. Bbahm {Ztschr. Angeic. Cliem., 27 

 (191i), No. 60, Aufsatzteil, pp. Jf64-Jf66) .—A discussion of the different protective 

 ferments and their value for diagnosing disease. 



