VETERINARY MEDICINE. 183 



Tuberculin, on account of its insufficient antigenic properties, is not deemed a 

 satisfactory tlierapeutic agent for treating tuberculosis in bovines. Antiphym- 

 atol is considered the best agent for curing tuberculosis which we have to-day. 



Tuberculosis. — A report of the results of the continued injections of 

 tuberculin upon tubercular cattle, S. B. Nelson (Washuigton Sta. Bui. llJf 

 (1914), PP- 3-15). — Impressed by the therapeutic work done with tuberculin 

 on man affected with tuberculosis, the author made a series of experiments to 

 study the effect of subcutaneous injections of tuberculin into cattle affected 

 with tuberculosis. The tests were made " under the conditions under which 

 the animals are generally kept; that is, a fairly well-kept stable in the winter 

 time, being outdoors a part of the daytime, and a run to pasture during the 

 summer months, being kept in the barnyard at night during this time." 



It was found that the injecticm into tubercular cattle of large monthly or 

 small weekly doses of tuberculin had apparently no therapeutic value. " The 

 injection of constantly increased daily or weekly doses of tuberculin apparently 

 does have therapeutic value. The evening temperature is usually higher than 

 the morning temperature in tubercular cows. The oftener tuberculin injections 

 are made into tubercular cattle, the sooner the temperature reaction begins and 

 the sooner the zenith is reached." 



The specific treatment of tuberculosis with Bruschettini's serum vaccine 

 (preliminary communication), A. Bruschettini (Ztschr, Titberkulose, 20 

 {1912), No. 1, pp. 43-48; ahs. in Centhl. Bakt. [etc.], 1. Aht., Ref., 58 {1913), 

 No. 7-8, p. 241)- — Bruschettini's serum was prepared by vaccinating animals 

 with lung extracts from tuberculinized animals, but particularly those animals 

 in which a hyperleucocytosis took place, and with an emulsion of fat-free 

 tubercle baccilli in hydrogen peroxid. The serum is given with a vaccine pre- 

 pared from tubercle bacilli which have been exposed to the action of living 

 leucocytes. 



The author hopes to give at the next International Congress of Tuberculosis 

 an account of the metliods of using the vaccine. 



Bovovaccine against bovine tuberculosis, A. Almgken (Svensk Vet. Tidskr., 

 18 {1913), No. 4, pp. 146-148; abs. in Ztschr. Inimunitdtsf. u. Expt. Ther., II, 

 Ref., 7 {1913), No. 13, p. 591). — Bovovaccine is deemed of service in combating 

 tuberculosis in bovines. 



Antiphymatol and phymatin of Klimmer as a means of combating' tuber- 

 culosis in bovines, C. Titze (Dent. Tierar~tl. Wchnschr., 21 {1913), No. 23, pp. 

 353-356; ahs. in Ztschr. Immuniidtsf. u. Expt. Ther., II, Ref., 7 {1913), No. 8, 

 pp. 365, 366). — On the basis of the experiments reported, in the literature 

 antiphymatol is deemed of no value for combating tuberculosis. Phymatin 

 does not seem to possess any advantages over Koch's old tuberculin. With the 

 ophthalmic reaction it is not possible to obtain in practice results which are 

 valuable for detecting the presence of tuberculosis. 



Bovine anaplasmosis in Arg'entina, J. Lignieres {Centhl. Bakt. [etc."], 1. 

 Aht., Oriff., 74 {1914), No. 1-2, pp. 133-162, figs. 5).— This is a detailed report 

 of investigations of anaplasmosis by the director of the Bacteriological Institute 

 of the Ministry of Agriculture at Buenos Aires. 



Anaplasmosis occurs endemically in certain regions in the north of Argen- 

 tina, from which it may be carried accidentally to other zones by infected 

 bovines, which serve as reservoirs for the virus. Anaplasuia argcntinum is of 

 the same type as A. marginalc, but a comparative study of the two is neces- 

 sary before definite conclusions as to their specific relation can be drawn. In 

 nature auai^lasmosis does not occur alone, but in connection with the piroplas- 



