180 EXPERIMENT STATION RECOED. 



study of the literature aud relates some of the author's experience with the 

 method. While the results obtained with serum from tuberculous subjects are 

 more satisfactory than the ones given by carcinomatous subjects, they are not 

 entirely reliable. 



Experimental transmission of Coccidium oviforme of the domestic rabbit, 

 A. LucET {Bid. ,Soc. Cent. Med. Vet., VO (1013), No. 2.'i, pp. ////f)--'/.5.?, figs. 5; 

 Compt. Rend. Aead. Sei. [Paris], 151 (WIS), No. 22, pp. lO'Jl, 1092).— The 

 author concludes that the two species of Coccidium described by Leuckart are 

 distinct, and that two forms of coccidiosis occur In the domesticated rabbit, 

 one, the hepatic form, caused by Eimcna stiedxe (C. cunieuJi, C. oviforme) ; 

 the other, the intestinal form, by E. perforans (G. perforans). 



Experimental study of coenurosis in the rabbit, A. Henry and A. CitrcA 

 (Ann. Inst. Pasteur, 28 (1914), A'O. 4, pp. 365-386; abs. in Rev. Bact., 4 {1914), 

 No. 2, p. 28). — Experimental infection of the rabbit with Cwnurus serialis, 

 which is the cystic stage of Tamia seriaUs of the dog, was obtained in from 40 

 to 50 per cent of the tests where young rabbits were used, if fertile segments of 

 the worm were selected and if the rabbits were fed with the segment without 

 other food. The cysts appear on about the eighteenth day and attain full de- 

 velopment within four months. 



A study of the serum of infected rabbits shows that it possesses properties 

 resembling those found in infection by the echinococcus. Precipitins are not 

 found in the natural disease, which the authors regard as being due to the 

 impermeability of the membrane, as precipitin appears after the escape of the 

 fluid into the tissues by operation or injection. Complement fixation tests 

 gave positive results in two out of ten cases of natural infection, and in all 

 four cases of experimental infection. The serum of infected rabbits produced 

 passive anaphylaxis in guinea pigs whether or not a positive complement 

 fixation reaction was obtainable. 



Degeneration of the islands of Langerhans associated with experimental 

 diabetes in the cat, J. Homans {Jour. Med. Research, 30 {1914), ^o. 1, pp. 

 49-68, pis. 3). — "The islands of Langerhans must be deeply concerned with 

 experimental pancreatic diabetes, for (a) the removal of more than three- 

 quarters of the pancreas of the cat, leaving the main duct in situ, usually 

 leads to a disappearance of secretory granules in the islands of Langerhans, 

 with suggestive evidence of over activity without the production of diabetes, 

 and (b) the same procedure occasionally causes a degeneration of the islands 

 of Langerhans accompanied by fatal diabetes without disturbance of the re- 

 maining acinous tissue." 



A bibliography of 23 titles is appended. 



In regard to the use of mallein, Mouili.eron {Bui. 8oc. Cent. M6d. Vet.. 91 

 {1914), ^0. 2, pp. 63-77). — A description of cases of glanders in which the 

 mallein test did not give a hyperthermic reaction. The hyperthermic reaction 

 of itself is not deemed suflicient to diagnose the presence of glanders, and it 

 is advisable to consider other clinical signs in condemning animals. It is also 

 recommended that a second mallein test be made. 



It is obvious that under conditions where hyi>erthermia is present the test 

 can not be used. 



A discussion of the paper by Drouin. Jacoulet, Bourg^s, Martel, Mouilleron, 

 aud Letard is included. 



The production of antirabic immunity by intraspinal injections of virus, 

 D. L. Harris {Jotir. Infeet. Diseases, 11 {1912), No. 3, pp. 397-401; ahs. in 

 Zentbl. Biochem. u. Biophys., 14 {1913), No. 19-20, p. 759).— It appears that by 

 giving one intraspinal injection of noninfectious dried virus to rabbits, a cer- 

 tain and rapid immunity can be jiroduced. 



