374 EXPERIMENT STATION RECORD. 



versal. The importance of eradicating the disease from the United States Is 

 emphasized. 



In regard to the transmission of foot-and-mouth disease to man through 

 the agency of milk, G. Schmidt (Berlin. Ticrdrztl. Wchnschr., 29 {1913), No. 

 42, pp. 71(9, 750). — A description of two cases in boys 5 and 7 years old, respec- 

 tively, who dranlc mi Hi from cows in a region where foot-and-mouth disease 

 was noted later. One of the cases was especially typical of the disease in ani- 

 mals. Two other possible cases in man are mentioned. 



The differentiation between nodules due to glanders and those caused by 

 parasites, V. A. Mooee and C. P. Fitch (Rpt. N. Y. State Vet. Col, 1912-13, 

 pp. 115-129). — ^A careful study of the material available and the findings of 

 others on the subject leads the authors to the following conclusions : 



" In the lungs of horses suspected of being glandered there are frequently 

 found nodules which are due to parasites. Similar nodules are occasionally 

 met with in other organs such as the liver, spleen, and lymphatic glands. These 

 parasitic nodules are frequently mistaken for those due to glanders {Bacterium 

 mallei.) Macroscopically it is difficult, often impossible, to differentiate be- 

 tween the nodules due to parasites and those caused by the glanders organism. 

 Mici'oscopically the lesions due to parasites are characterized by a variable 

 eosinophilic infiltration. Eosinophils are occasionally found associated with 

 other lesions such as those of miliary tuberculosis, malignant tumors, and some 

 others. Ebhardt found eosinophils associated with old glanders nodules. Their 

 presence was probably due to stimuli other than B. mallei. When eosinophils 

 are found in the microscopic examination of nodules from the lungs of sus- 

 pected glandered horses, the lesions should not be considered as the direct 

 result of glanders infection." 



A bibliography of 23 titles is appended. 



A new method for the diagnosis of glanders. — The intrapalpebral mallein 

 reaction. — Preliminary note, A. Lanfranchi {Mod. Zooiatro, Parte Set, No. 

 1 {1914), pp. 1-5, figs. 2). — ^This is a combination of the subcutaneous and 

 ophthalmic reaction. It consists of injecting 0.25 cc. of crude mallein dissolved 

 in 2.5 cc. of normal (physiological salt solution between the skin and mucous 

 membrane of the lower eyelid. The usual iirophylactic precautions are observed 

 before the injection. After two hours or so the blood vessels of the conjunctiva 

 become highly injected, a mucopurulent discharge begins to form, and the 

 lower lid becomes swollen, reaching its maximum after 12 to 24 hours. It then 

 also involves the upper lids and exterior of the arch of the zygoma. The reac- 

 tion lasts from 48 to 72 hours. Constitutional effects such as rise in temper- 

 ature ( thermoreaction) are also present. 



Notes on osteomalacia (bone chewing) {Dept. Agr. N. S. Wales, SeL Biil. 12 

 {1914), pp. 23). — In addition to an introduction by F. B. Guthrie, this bulletin 

 contains three papers, namely, A Note on the Nature and Causation of Oste- 

 omalacia in New South Wales, by M. Henry (pp. 5-7), The Osteomalacia Soils 

 of the South Coast Districts, by H. I. Jensen (pp. 7-15), and Investigations 

 Undertaken in Connection with " Osteomalacia " or " Bone Chewing Disease " 

 on the South Coast, by A. A. Ramsay (pp. 1&-23). 



Immunizing with dead trypanosomes, K. Aoki and H. Kodama {Ztschr. 

 Immuniiatsf. u. Expt. Titer., I, Orig., 18 {1913), No. 6, pp. 693-700).— In these 

 experiments it was not possible to immunize rabbits, rats, and mice by pretreat- 

 ment with suspensions of dead trypanosomes against a succeeding - infection 

 with dourine trypanosomes. It was also not possible to immunize rats and 

 rabbits with large amounts of dried trypanosomes, 



Nephroparatyphoid and nephrotyphoid, C. Klienebebgeb {Berlin. Klin. 

 Wchnschr., 51 {1914), ^o. 21, pp. 969-972, figs. 2).— A description of two cases 



