376 EXPERIMENT STATION RECORD. 



to render them noninfectious. Tlie possibility of giving local treatment of 

 tuberculosis is pointed out. 



Dogs, which are more sensitive to human than to bovine tubercle bacilli, 

 can be easily inmiunized by bacteria which have been subjected to the process 

 of dry heating and given intraperitoneally or intravenously. After receiving 

 100 nig. of dry heatetl bacteria they can withstand an injection of from 250 

 to 300 mg. of living bovine tubercle bacilli. Tests were made with highly 

 potent dog sera on guinea pigs but with unsatisfactcn-y results. Better results 

 were obtained with sera prepared in rabbits with the human type of tubercle 

 bacillus. Guinea pigs were immunized against a slightly virulent strain of 

 the human type of tubercle bacillus which had been gradually treated with 

 trysin. This treatment increased the length of life of these animals but did 

 not confer a complete immunity. 



Investigations about the tubercle bacilli content of the feces, the blood, 

 and the milk of cows affected with open tuberculosis, M. Gressel {Unter- 

 suchungen iiber den TuberkclhaziUcngeliaU tier Faeces, des Blutcs und der 

 Milch von Kiihen, welche an offener Lungentuherlmlose leiden. Inaug. Diss., 

 Giessen, 1913, pp. 64; abs. in MiiticJien. Tierdrztl. Wchnschr., 57 (1913), No. 33, 

 pp. 625, 626). — In the feces of 13 bovines affected with open tuberculosis 

 tubercle bacilli were noted six times by the animal inoculation test. The mere 

 detection of acid-fast bacilli in the feces by the microscopical method does not 

 point conclusively to tubei'culosis. The blood of animals affected with a high 

 grade of open tuberculosis does not as a rule contain tubercle bacilli. In four 

 out of 12 cases bacilli were found by the microscopical method but not with the 

 animal test. As a rule bovines with advanced tuberculosis without involvement 

 of the udder do not discharge tubercle bacilli with milk, and tubercle bacilli 

 were found in the milk of only one out of 12 animals. 



The value of the tuberculin eye test, W. Konge (Berlin. Tierdrztl. 

 Wchnschr., 29 {1913), No. 45, pp. 800, 801). — ^The conclusion reached, based on 

 data obtained by testing 21 cows, healthy and tubercular, is that a purulent 

 conjunctivitis obtained after injecting phymatin is diagnostic of tubei-culosis. 



Udder diseases and the differential diagnosis of mammary gland tuber- 

 culosis, Seiler (Deut. Tier^rstl. Wchnschr., 21 (1913), No. 31, pp. 449, 500; 

 abs. in Centbl. Balct. [etcl, 1. Abt., Ref., 59 (1913), No. 11, p. 349).— A case, 

 believed to be a pyobacillosis of the mammary gland with metastasis in the 

 lymphatic organs, is described. Tuberculosis was absent. 



Diplodinium ecaudatum, with an account of its neuromotor apparatus, 

 R. G. Sharp (Univ. Cal. Pubs., Zooh, 13 (1914), No. 4, pp. 43-122, pis. 5, figs. 

 4). — ^This paper deals with the morphology of D. ccaiidation, including D. 

 ecaudatum and D. cattanci, together with a description of three new forms of 

 this species, all of which are found in the first and second divisions of the 

 stomach of western cattle. 



Investigation into the morphology and life history of Onchocerca gibsoni, 

 A. Breinl et al. (Aust. Inst. Trop. Med. Rpt. 1911, pp. 5-17). — ^The authors' 

 observations indicate that the worm nodules occur most frequently behind the 

 femoro-tibial joint. Careful examination of the internal organs, including the 

 spleen, liver, heart, etc., failed to reveal the presence of any parasite akin to O. 

 gibsoni. The fact that nodules occur in those parts of the animals which come 

 in contact with the ground when the beast is resting, or with water when the 

 cattle enter it for drinking or cooling purposes, namely, in the brisket and 

 behind the femoro-tibial joint, is considered an important aid in the search 

 for the means of transmission from host to host. 



