580 EXPERIMENT STATION RECORD. 



(pp. 242-240) ; and Foot-and-Moutli Disease in New York State. 1914. by J. G. 

 Wills (])p. 251-2.55). 



The foot-and-mouth disease, what it is, what it does, how to fight it, and 

 how to prevent it (Garden City, N. Y.: Doubleday, Page d Co., 191Jf, pp. 19, 

 figs. 6). — This pamphlet embraces several articles, namely, Every Farmer's 

 Duty in the Present Foot-and-Moutb Crisis, by V. A. Moore (pp. 3-7) ; Foot- 

 and-Mouth Disease, Its Nature, Symptoms, Effects, and Treatment (pp. 8-16) ; 

 and Historical Notes and Data Concerning the Disease in This Country and 

 Abroad (pp. 17-10). 



Foot-and-mouth disease [in the United States] {Amer. Vet. Rev., ^6 (1915), 

 No. 4, pp. 380-397). — This is a discussion of the outbreaks of foot-and-mouth 

 disease that have occui'red in this country. 



About the utilization of the conglutination reaction as a diagnostic test 

 for glanders, C. W. Andersen (Ccntbl. Balct. [etc.], 1. Aht., Orig., 72 (1913), 

 No. Jf-5, pp. 394-398; abs. in Berlin. Tierarztl. Wchnschr., 30 (1914), No. 7, p. 

 124). — The conglutination reaction (E. S. R., 28, p. 478) was studied with the 

 sera from 225 horses. Parallel tests were run with the complement fixation 

 method. 



Fourteen of the sera reacted positively, and in 13 of the horses on section 

 glanderous lesions were noted. In the fourteenth horse some old nodules were 

 found in the lung. The complement fixation and the mallein tests showed posi- 

 tive in the latter case. Four sera gave partial fixation in the complement bind- 

 ing test but negative findings with the conglutination test. The four horses 

 were found sound on autopsy. Two hundred and one sera gave negative com- 

 plement fixation and conglutination reactions. The author believes the con- 

 glutination test is more sensitive and specific for diagnosing glanders than the 

 complement fixation test. This work supports the findings of Sti'anigg. 



The ophthalmic test in the diagnosis of glanders, F. Favero (J/0(f. Zooiatro, 

 Parte Sci., 25 (1914), No. 2, pp. 49-63; abs. in Jour. Compar. Path, and Ther., 

 27 (1914), No. 3, pp. 207-269).— "The ophthalmic test does not always clearly 

 indicate the existence of glanders. A positive ophthalmic test is specific. It is 

 essentially a muco-purulent secretion which persists for at least 24 hours. In 

 doubtful cases the ophthalmic test reiieated at a sliort interval gives confirma- 

 tory results. In a positive reaction there is a high percentage of neutrophile 

 polynuclear leucocytes in the conjunctival exudate, but this character Is not 

 specific." 



An ophthalmic mallein eye dropper, W. Wilson (Amer. Vet. Rev., 46 

 (1914), ^0. 1, p. 62, figs. 3). — The apparatus consists of an ordinary medicine 

 dropper with the point drawn out and bent at right angles. The tip of the 

 dropper is fitted into a notch made in a camel's-hair brush just next to the hair, 

 and the dropper is fastened by means of a clamp made from a thin piece of 

 sheet copper. " By filling the dropper with mallein. which easily holds 10 to 

 20 doses, it may be squeezed out into the brush and placed into the eye, and any 

 remaining in the dropper after the testing is completed may be returned to the 

 bottle without being badly contaminated." 



Simultaneous method of inoculating cattle and carabaos with serum from 

 animals that have been recently immunized, A. R. Ward and F. W. Wood 

 (Philippine Jour. Sci., Sect. B. 9 (1914), No. 1. pp. 125-135. pis. 5).— Experiences 

 with the simultaneous inoculation method utilizing blood dra\\Ti in the field 

 have demonstrated " that there is no necessity for maintaining an expensive 

 permanent laboratory and herd for the production of artiriuderi)est serum from 

 hyperimmunized animals. A radical reduction in the cost of serum production 

 has been effected, and in consequence the possibility of extensive employment 

 of simultaneous inoculation in combating rinderpest has been demonstrated," 



