678 EXPEBIMENT STATION EECOBD. 



yet but they are not encouraging, on the other hand they lead to the belief that 

 these injections may result injuriously in some cases and henelicial in others." 



Annual report of the Bengal Veterinary College and of the Civil Veterinary 

 Department, Bengal, for the year 1913—14, A. Smxth and P. J. Kerr (Ann. 

 Rpt. Bengal Vet. Col. and Civ. Vet. Dcpt., 1913-1/t, pp. 6+///+y+r///+3).— 

 This is the usual annual rei)ort (E. S. II., 30, p. 778). 



E. Merck's annual report of recent advances in pharmaceutical chemistry 

 and therapeutics (Merck's Ann. Rpts., 21 (1913), pp. 589). — This is a review of 

 the literature pertaining to these topics for the year 1913. Siiecial articles on 

 nucleiu and nucleic acid and preparations used for radiographic examinations 

 are included. A bibliographic index is al)pended. 



Bacterial antiferments. — Studies on ferment action, XVII, J. W. Jobling 

 and W. I'KTKKSEN (Jour. Expt. Med., 20 (191',), No. .5. pp. .)r)2-J,Gl, figa. 2).— 

 This work was done with several kinds of bacteria, including (he tuliercle 

 bacillus. Intact bacteria are said to resist digestion by trypsin because no 

 protein substratum is exposed. Dried organisms resist digestion in a degree 

 proportional to their content of unsaturated lipoids. Lipoidal extractives were 

 found to I'educe the resistance to tryptlc digestion. 



"The extracted lipoids (saponified) are antitryptic in a degree proportional 

 to their unsaturation. The inactivation of the antiferment in Gram-negative 

 organisms is probably due to changes in the degree of lipoidal dispersion. Bac- 

 teria adsorb lipoids from the serum when incubated at 37° C. Such organisms 

 when dried are found to be more resistant to tryptic digestion than untreated 

 organisms." 



Lipoids as inhibitors of anaphylactic shock. — Studies on ferment action, 

 XVIII, J. W. Jobling and W. Peiersen {Jour. Expt. Med., 20 {WW, No. 5, 

 pp. Jf68-i76, fiff. 1). — "The antitryptic titer of the serum can be increased by 

 .subcutaneous injections of serum lipoids (antitrjiJsin) and of the liiwids from 

 egg yolk. Animals so injected show a relative immunity to acute anaphylactic 

 shock (two minimum lethal doses). Extraction of lipoids contained in antigens 

 increases the toxicity of the antigen when injected into a sensitized anijnal. 

 Sublethal doses of soap solutions injected simultaneously with the antigen 

 (purified horse serum albumin) prevent anaphylactic shock. The refractory 

 state following anaphylactic shock is related in part to an increase in the 

 antitryptic tiler of the serum." 



An anomalous strain of Bacillus paratyphosus (B) and its source, 11. J. 

 HuTCHENs and W. J. Tulloch (Ahs. in Jour. Path, and Bact., 18 (1914), ^'o. 3, 

 pp. 431, Jf32). — ^An organism was Lsolatetl from brewers' yeast which had been 

 used as a feed for various siiecies of farmyard animals in which it appears to 

 have produced symptoms of acute enteritis. The organism exhibited the usual 

 mon>hological and biochemical characteristics of the Salmonella group but dif- 

 fered in its agglutination reactions. 



Report on the investigation of four cases of sudden death which took 

 place at the Athens State Hospital, E. R. Hayhxjrst and E. Scott (Mo. Bui. 

 Ohio Bd. Health, J, (191//), No. 10, pp. l-'f07-U21, fig. i).— Autopsical findings 

 are presented for four men, patients with minor degrees of psychoses at the 

 Athens State Hospital, and 31, 56, 56, and 67 years old. respectively, who were 

 suddenly asphyxiated within five minutes after entering a new metal silo being 

 filled with corn silage. The men were employed to tramp down the silage, and 

 were waiting for work to begin. In spite of efforts at resuscitation, including 

 hypodermic injections of stimulants, it was impossible to revive any of them. 



On (he morning following the accident tests were made in the silo with 

 guinea pigs, rabbits, and dogs, which succumbed in a few minutes. About half 



