878 EXPERIMENT STATION RECORD. 



have been bitten by ticks. Under experimental conditions by no means every 

 tick bite produces paralysis in laboratory animals. A weak extract of ticks 

 will not cause paralysis when injected into white rats, even though it possesses 

 definite power to prevent the coagulation of blood." 



Is the detection of tubercle bacilli in the blood of value in diagnosis? 

 Baetge (Dent. Med. Wchnschr.. JfO (19 Uf), No. 12, pp. 591-593; abs. in Berlin. 

 Tierdrztl. Wchn-schr., 30 {191 Jf), No. 18, p. 308). — This inve.stigation. made on 

 man. led to the conclusion that blood examinations made with the object of 

 finding tubercle bacilli were of no value, even with the severe cases where the 

 subjects died a short time thereafter. 



Determination of tubercle bacilli in the urine, E. Gautieb (Jour. Vrologie, 

 5 (1914), No. 2, pp. 161-170; abs. in Jour. Amer. Med. Assoc, 62 (1914), No. U, 

 p. 1125). — The Ziehl-Neelson technique is regarded as absolutely reliable for 

 detecting tubercle bacilli in the urine, provided the dt^oloration is done with 

 extreme care with 33 per cent nitric acid and with alcohol. 



" The method requires much patience, long centrifuging with plenty of 

 fluid, and the slides must be examined all over. If the first examination gives 

 negative findings, the procedure must be repeated with urine voided a few 

 hours later. If a specimen stained with methylene blue shows red corpuscles, 

 degenerated polynuclears, but no microbes, the search for tubercle bacilli must 

 be i-esumed with renewed energy." 



The findings in 28 cases are briefly summarized. 



The incidence and bacteriological characteristics of tuberculous infection 

 in children, A. Eastwood and F. Griffith (Rpts. Local Govt. Bd. [Gt. Brit.]. 

 Pub. Health and Med. Siibjs.. n. ser., No. 88 (1914), PP- 1-104, pis. 6; abs. in 

 Jour. Compar. Path, and Ther., 27 (1914), No. 1, pp. 80-83).— The object of this 

 work was to determine the incidence of tuberculous infection in 150 children 

 between the ages of two and ten years dying from various causes. 



The results are said to supplement those obtained by the Royal Ck)mmission 

 on Tuberculosis (E. S. R., 25. p. 884; 26. pp. 884-886). In 56 cases there was 

 no evidence of tuberculous infection, but in the remaining 94 evidence of in- 

 fection was found, and in the majority of cases the formation of visible tuber- 

 culous lesions from which the bacilli could be recovered in culture was noted. 

 In 16 of these cases, although tuberculous lesions were present, the bacilli were 

 apparently dead. Examples of latent tubercle bacilli in the mesenteric or 

 bronchial lymph glands of children showing tuberculosis in some other parts 

 of the body were noted in 22 cases. In five these were of the bovine type 

 and they were lodged in the mesenteric glands once and in the bronchial glands 

 four times. Bovine bacilli were noteti in three cases in apparently healthy 

 parts, once in the bronchial and twice in the mesenteric glands; and the 

 human type of bacilli twice, in one from the cervical, bronchial, and mesenteric 

 glands, and in the other from only the mesenteric glands. Death was due to 

 tuberculosis in 61 cases. 



In 16 cases the bacilli present in the lesions could not be classified as to 

 type, but of the 78 cases remaining, 65 were due to the human type and in 52 

 of these tuberculosis was the cause of death. The bovine type was responsible 

 for the infection of 13 cases, and death followed in nine of them. 



It is pointed out that distal lesions without lesions at the portal of entry 

 were exceedingly rare. The uncertainty of conducting feeding experiments 

 with animals and small doses of bacilli is emphasized. 



An inquiry, based on a series of autopsies, into the occurrence and distri- 

 bution of tuberculous infection in children, and its relation to the bovine 

 and the human types of tubercle bacilli respectively. A. S. Griffith (Rpts. 

 Local Govt. Bd. [Gt. Brit.], Pwb. Health and Med. Subjs., n. aer., No. 88 (1914), 



