880 EXPERIMENT STATION RECORD. 



spite of proper treatment, probably means a hopeless prognosis. Its absence is 

 generally, though not Invariably (regardless of how sick the patient seems), 

 of good prognostic import. Its prompt and continued disappearance soon after 

 treatment is instituted, in a patient who showed it before treatment, so far as 

 our experience goes, is a favorable prognostic sign ; but it will take several 

 years' observation of these particular patients to determine this point con- 

 clusively. 



" Finally, it is not an invariable guide to prognosis, but in the majority of 

 cases is of much value, and as all prognoses must be good, bad. or doubtful, it 

 will, if judicially used, help materially to reduce the number in the doubtful 

 class." 



Curative tests against tuberculosis, Velasko {Milnchen. Tierdrztl. Wchnschr., 

 65 (1914), No. 11, pp. 2^8. 21t9). — A six-year-old ox having typical clinical signs 

 of pulmonarj' tuberculcsis was given two injections of Burow's tuberculosan 

 with the result that the animal in one-half year's time could have been sold to 

 a butcher at a profit. A young cow having the clinical signs of tuberculosis and 

 also giving a positive opthalmic reaction was ti'eated with three doses of Klim- 

 mer's antiphymatol. Five months later all signs indicating a pathological con- 

 dition had vanished. 



The destruction of the vitality of Cysticercus bovis by freezing, B. H. 

 Ransom {Jour. Par., 1 (1914), No. 1, pp. 5-9). — Experiments conducted by the 

 author show that if measly beef carcasses are exposed for six days to a tem- 

 perature not exceeding 15° F. the vitality of the cysticerci will be destroyed; 

 " that some may survive in carcasses exposed for five days to this temper.^ ture. 

 though it is doubtful whether they will retain sufficient vitality to develop in 

 the human host; and finally that a considerable proiwrtion may survive in car- 

 casses exposed to a temperature of 1'5° for four days or less." 



Under the new regulations governing the inspection of meat (E. S. R.. 32, p. 

 777), instead of being refrigerated for three weeks as heretofore carcasses re- 

 tained on account of C 'bovis, of which there have been more than 40,000 

 annually, will be held for six days at a temperature not higher than 15" and 

 then released for food. Thus the refrigei'ation expense will be greatly reduced 

 since only about a third as much cold will have to be produced for each carcass 

 and only about a third as much storage space will be required to take care of 

 the carcasses. 



References to the literature are appended. 



Division of veterinary science, M. H. Reynolds {Minnesota Stn. Rpt. 1914. 

 pp. 49-55). — The total loss in the State from hog cholera, both direct and indi- 

 rect, is estimated at not less than $5,000,000 for the year. The production of 

 serum increased from 25.000 cc. in 1908 to 1.000.000 cc. in 1913. 



An investigation of several proprietary hog-cholera cures and preventives 

 showed that Benetol apparently has no immunizing value when given to healthy 

 hogs exposed to infection and has no curative value when administered to hogs 

 in different stages of the disease. When given internally by drench, unless 

 highly diluted, it is irritating to the mucous membranes of the alimentary tract 

 and when injected intramusculai'ly is followed by extensive abscess formation. 

 In a similar series of exiieriments Hudson Hog Cholera Remedy gave very 

 unsatisfactory results, and preliminary trials with Hog Cholera Specific were 

 in no way encouraging and were discontinued entirely when analyses showed 

 that the so-called remedy consisted of a small amount of potassium iodid. 



The standardization of antihog-cholera serum, T. P. Haslam and O. M. 

 Franklin {Jour. Infect. Diseases, 15 (1914), No. 2, pp. 251-261. fig. i).— The 

 object of this investigation was to ascertain if the various sources of error 

 affecting tlie methods of standardization of antihog-cholera serum may be re- 



