1917] VETERINARY MEDICINE. 77 



0.004 cc. of rabbit serum given subcutaneously. Twenty-one days later 0.2 cc. 

 of coli-agglutinating rabbit serum was given intracardially. The sensitized 

 animal displayed moderate anaphylactic symptoms, while the control did not 

 react. Samples of blood were lalien from the hearts of both control and experi- 

 mental animals five minutes and two hours after injection and the agglutinin 

 titer determined. The blood of the sensitized animal showed an agglutinin 

 content higher than that of the control animal five minutes after reinjection, 

 and a lower content than that of the control two hours later. 



It is concluded in general that " a foreign serum disappears more quickly 

 from the blood of an animal sensitized to that serum than from that of a 

 normal animal. It disappears more quickly from the blood of highly reacting 

 animals than from that of slightly reacting animals." The individual varia- 

 tion and the need of results from a large number of animals to give definite 

 conclusions is indicated. 



The antigenic properties of ^-nucleoproteins, H. G. Wells {Jour. Biol. 

 Chem., 28 {1916), No. 1, pp. 11-16). — The results of the study reported are sum- 

 marized as follows : 



The so-called /3-nucleoproteins obtained from rarious tissues by extracting 

 with boiling water possess definite antigenic properties demonstrable by the 

 anaphylaxis reaction. As there are but few known proteins that retain their 

 antigenic capacity after boiling, this observation may indicate something as to 

 the nature of the protein complex of /3-nucleoproteins. The proteins of 

 o-nucleoproteins are. on the contrary, very susceptible to chemical and physical 

 changes. /3-Nucleoproteins from beef pancreas, beef spleen, and pig pancreas 

 seem to be similar but not identical, as far as can be determined by the 

 anaphylaxis reaction. 



See also a previous note (E. S. R., 32 p. 179). 



Transformation of pseudoglobulin into euglobulin, W. N. Beso {U. S. 

 Dept. Agr.. Jour. Agr. Research, 8 {1917), Xo. 12, pp. JfJ^9-Jt56). — As indicated 

 by Banzhaf.^ the author presents evidence of a transformation of pseudo- 

 globulin into euglobulin from data obtained in the concentration of anthrax, 

 diphtheria, and tetanus sera when the sera were heated at 60° C. in the pres- 

 ence of 30 per cent saturated ammonium sulphate. It is noted that the amounts 

 transformed were considerable in some instances, while in one ca.se the amount 

 was so small as to indicate that there was no transformation at all. 



The experimental technique used was that described by Eichhorn, Berg, and 

 Reiser (E. S. R., 36, p. 577). 



The failure of Homer (E. S. R., 35, p. 680) to observe any transformation of 

 pseudoglobulin into euglobulin is considered by the author as probably due to 

 the use of analytical technique that was not delicate enough to detect such 

 slight transformation, and to errors incidental to the handling of large amounts 

 of serum mixtures. 



Weyl's handbook of hygiene: Meat inspection, edited by C. Fkaenken 

 {WeyVs Handbuch der Hygiene: Fleishbeschau. Leipsig: Johann Amhrosius 

 Barth, 2. ed., lAeferung 23 {1915), pp. IX-227, figs. 53).— In this part of the 

 8-volume Handbook of Hygiene meat inspection is dealt with by R. Edelmann. 

 A work by the author on the subject has previously been noted (E. S. R., 3.5, 

 p. 879). 



Are uniform regulations feasible among the different American countries 

 for the prevention of the introduction and dissemination of diseases of ani- 

 mals? A. D. MEL^^^r {Jour. Amer. Vet. Med. Assoc, 50 {1916), No. S. pp. 361- 

 366). — This is an abstract of a paper in which the author calls attention to the 



iCoUected Studies Bur. Lab. Dept. Health N. Y. City, 7 (1912-13), pp. 114-116. 



