1917] VETERINARY MEDICINE, 275 



The procedures are described in detail, discussed, and some experimental 

 data submitted. See also a previous note by Kolmer, Schamberg, and Raiziss 

 (E. S. R., 36, p. 679). 



The differentiation of the paratyphoid-enteritidis group, I, E. O. Jordan 

 (Jour. Infect. Diseases. 20 (1917), Xo. 4, pp. J,57-4S3).—The cultures of bacilli 

 belonging to the paratyphoid-enteritidis group that were examined by the 

 author and are here considered fall into four subdivisions, namely, Bacillus 

 paratypliosus A, B. paratyphosus B, B. suipestifer, and B. enteritidis. 



The enzyms of the tubercle bacillus, H. J. Coepek and H. C. Sweany (Jour. 

 Biol. Chcin., 29 {1911), No. 2, pp. XXI, XXII).— It is noted that tubercle 

 bacilli, both human and bovine, posse.ss autolytic enzyms, as is indicated by 

 the liberation at incubator temperature of noncoagulable nitrogen and amiuo- 

 acid a-nitrogen after the organisms have beeen killed by toluene and chloro- 

 form. The bacilli themselves, or autolyzates therefrom, also possess a trypsin- 

 like enzym capable of cleaving proteins in alkaline solution, a weak pepsin- 

 like enzym active in acid solution, an erepsin-like enzym capable of cleaving 

 peptone in acid solution, a nuclease which acts on nucleic acid, and a urease. 

 No .starch-hydrolyzing or saccharose-inverting enzyms or enzyms capable of 

 digesting elastic tissue prepared from lamb's lung or connective tissue prepared 

 from tubercles could be demonstrated by the methods used for detecting these 

 enzyms. It is indicated that the demonstration of the latter enzyms must be 

 by indirect methods, and the results are therefore not conclusive. 



The immune reaction to tuberculous infection, R. AVeil {Jour. Amer. Med. 

 Assoc, 68 {1911), No. 13, pp. 912, 913, figs. 2).— From some data obtained by 

 suspending the uterus from a sensitized animal in Locke's solution and deter- 

 mining the effect of the antigenic substance on its muscular contractions, the 

 author indicates that " it is clear that these antibodies musrt be considered 

 to be cellular or ' sessile,' since it is only on this theory that the response of 

 the isolated organ can be explained. It is not to be supposed that the uterine 

 cells are the only ones of the body which contain the specific antibodies. In 

 fact, it is highly probable that many, if not all, of the tissues of the body are 

 similarly altered by tuberculous infection. ... If this be the case, it seems 

 highly probable that the various types of altered reaction, . . . whether local 

 or general, are to be explained on the basis of cellular sensitization to the 

 agent of the disease and to its products. The details of the mechanism of 

 these reactions, as well as of the partial immunity of the infected animal, will 

 perhaps be found to correspond to analogous conditions in general anaphylaxis." 



The treatment of experimental tuberculosis in guinea pigs and rabbits 

 by taurin, alone and in combination with gold chlorid and sodium oleate, 

 M. Takeoka {Jour. Infect. Diseases, 20 (1911), No. 4, pp. ^42-^50). —Experi- 

 mental data of a study of the curative value of taurin alone or in combination 

 with a colloidal mixture of sodium gold chlorid and sodium oleate in experi- 

 mental tuberculosis in guinea pigs and rabbits are reported. The guinea pigs 

 were infected with either bovine or human strains of the organisms, the results 

 being similar in both cases. 



In general the control animals died before any of the treated animals, and 

 whereas the controls lost weight almost uniformly, the treated animals gained. 

 The majority of the treated animals were killed for observation many days 

 after the controls had died, and the contrast in the extent of visible tuberculosis 

 was marked. While the process was found to be advanced in the controls, it 

 was arrested and in some instances apparently cured in the treated animals. 



Rabbits were infected with intraperitoneal or intravenous injections of the 

 bovine strain. The treatment was carried out by intravenous injections of 



