19181 VETERINARY MEDICINE. 383 



that the injection of placenta does not increase the general or call forth the 

 specific proteoclastic ferment of the hlood." 



See also a previous note (E. S. R., 35, p. 179). 



The "Wassermann reaction in rabbits after injection with luetic liver 

 extracts, H. Eiken (Ztschr. Immunitdtsf. u. Expt. Ther., I, Orig., 24 (1915), 

 No. 2, pp. 188-19S). — The injection of aqueous extracts or emulsions of luetic 

 liver into rabbits yielded positive Wassermann reactions sooner or later, depend- 

 ing on the individuality of the extract. The reaction, in general, disappeared 

 rather rapidly, but could often be obtained months after the injection. The same 

 results were obtained by using an alcoholic extract of an aqueous extract of 

 luetic liver. These results confirm the findings of earlier investigators. 



A positive Wassermann reaction could not be obtained, hov^^ever, by the in- 

 jection of an alcoholic extract of human heart or an aqueous extract of the 

 liver of nonsyphilitic children. 



If the aqueous extracts were passed through a Chamberland filter their 

 antigenic value was greatly reduced. 



Some poisonous plants of Idaho {Idaho Sta. Bui. 86 {1916), pp. 16, figs. 7). — 

 Brief descriptions are given of some of the more important poisonous plants 

 of Idaho by F. W. Gail and some suggested remedies by A. R. Hahner. 



Prevention of losses of live stock from plant poisoning', C. D. Maksh 

 {U. S. Dept. Agr., Farmers' Bui. 120 {1916), pp. 10). — This supersedes Farmers' 

 Bulletin 536, previously noted (E. S. R., 29, p. 280). It is pointed out that 

 while something may be accomplished by the application of medical I'emedies 

 to sick animals the main reliance in reducing losses must be upon careful man- 

 agement of the range and the animals upon it. Such " management should be 

 directed to the destruction of the poisonous plants in some cases; the use of 

 the range when the plants are not poisonous in other cases ; the allotment of 

 some ranges to animals not affected by the plants ; care in driving live stock 

 and bedding places for sheep ; the elimination of fixed driveways ; and to ' rota- 

 tion ' in the use of the range." 



Acidosis and cotton-seed meal injury, C. A. Wells and P. V. Ewing (Oeorgia 

 Sta. Bui. 119 {1916), pp. 35-64, fiffs. 2). — An account is given of the performance 

 and results of an investigation conducted at the station during 1914 and 1915, 

 the object of which was to determine the excess of acid-forming over base- 

 forming elements in cotton-seed meal, and whether such excess causes the 

 injury of pigs which have eaten large quantities of the meal. 



The literature relating to the subject is first reviewed, in connection with 

 which is given a bibliography of 215 titles. The investigation, which is reported 

 in detail and includes much tabular data, is summarized as follows : 



" One hundred gm. of cotton-seed meal contained an excess of acid-forming 

 over base-forming elements equivalent to 8.21 cc. normal acid. A 30 to 40 

 day lethal dose of the cotton-seed meal was found to be 25 gm. of meal per 

 kilogram live weight daily for 6-weeks-old pigs, weighing 6 to 10 kg. each, in 

 the type of ration here fed. In feeding cotton-seed meal to ascertain its degree 

 of injury, it seemed necessary to balance the ration, not so much as regards 

 the nutritive ratio, but rather as to the necessary food factors, with some such 

 substance as skim milk. The injury was manifested before death by rather 

 constant abnormal physical and metabolic processes. As much as twice the 

 mineral acid represented by the excess acid in a provisional lethal dose of cot- 

 ton-seed meal did not injure the pigs, though it produced the metabolic changes 

 characteristic of acidosis. 



" Under the influence of cotton-seed meal injury the pigs did not deflect 

 ammonia from urea formation to neutralize any excess acid in the food. The 

 feeding of sodium bicarbonate did not prevent the injury. Addition of ferrous 



