666 EXPERIMENT STATION RECORD. [Vol.35 



that glucal is so closely related to glucose and may possibly be an intermediate 

 stage of glucose metabolism. In addition to studying the chemical character- 

 istics of glucal, experiments were carried out with various laboratory animals 

 which showed that glucal is not toxic, produces no effect on blood pressure or 

 on respiration when injected intravenously in moderate quantities, and is not 

 completely metabolized by the animal body when injected at the rate of 0.9 

 gm. per kilogram of body weight per hour. 



The lipoids C' fat ") of the blood in diabetes, W. R. Blooe, E. P. Joslin, 

 and A. A. Hornok {Jour. Biol. Chem., 26 {1916), No. 2, pp. 417-430) .—The ob- 

 servations here reported show in part that " in severe diabetes the biocd 

 lipoids were all markedly increased, up to 100 per cent or more of the normal 

 values. In mild diabetes the lipoids may be normal. In general, the more 

 severe or long standing the diabetic condition, the more marked was the ab- 

 normality in the blood lipoids. 



" In spite of the high values, the relations between the lipoids were prac- 

 tically those of normal individuals, indicating that the fat metabolism was 

 essentially normal." 



For earlier work, see previous notes (E. S. R, 34, pp. 562, 563). 



Pellagra — a critical study, J. Aulde (Med. Rec. [N. y.], 90 {1916), No. 5, pp. 

 181-185). — The author advances the theory that the essential factor in the 

 production of pellagra, scurvy, and beri-beri is the mineral deficiency in the 

 protein molecule, and that calcium depreciation is responsible for pellagra. 



Preliminary observations on metabolism in pellagra, A. Hunter, M. H. 

 GivENS, and R. C. Lewis {Pub. Health Serv. U. S. Hyg. Lab. Bui. 102 {1916), 

 pp. 39-67). — Data are given regarding the amount of indican excreted and the 

 nitrogen balances in the case of a number of inmates of the pellagra hospital at 

 Spartanburg, South Carolina. 



Pellagra. — The value of the dietary treatment of the disease, J. R. Ridlon 

 {Pub. Health Rpts. [U. S.], 31 {1916), No. 30, pp. 1979-1999).— This report is 

 based on observations upon 58 pellagra patients in the U. S. Marine Hospital at 

 Savannah, Ga. The patients were given a diet relatively rich in animal and 

 leguminous protein component and relatively poor in nonleguminous-vegetable 

 component. It is concluded from these cases that the dietectic treatment of 

 pellagra is of paramount importance, and " that in this series success has fol- 

 lowed the use of a diet in which the animal and leguminous-protein component 

 has been relatively increased and the nonleguminous-vegetable component 

 relatively decreased." 



As a part of the histories of the pellagra patients an attempt was made to 

 ascertain the diet consumed during the three months previous to the appear- 

 ance of the disease. The data collected from 35 patients are reported in this 

 article. "A study of these diet histories shows that the vegetable and fat com- 

 ponents were notably conspicuous and that the animal protein foods were rela- 

 tively inconspicuous." 



The energy metabolism of a cretin, F. B. Talbot {Amer. Jour. Diseases 

 Children, 12 {1916), No. 2, pp. 145-148, fig. 1).— The heat production of a cretin, 

 3 years 8 months old, was determined by the calorimeter to be 898 calories per 

 square meter of body surface, or 40.5 calories per kilogram body weight. 



ANIMAL PEODIJCTION. 



Meat situation in the United States, I-IV {U. S. Dept. Agr. Rpts. 109 

 {1916), pp. 307, pi. 1, figs. 31; 110 {1916), pp. 100, pis. 6; 111 {1916), j)p. 64, pls. 

 5, figs. 2; 112 {1916), pp. 27). — This portion of the report is treated in four 

 parts. 



