882 EXPERIMENT STATION RECORD. [Vol.35 



Serum osmose. The treatment of wounds by blood serum obtained through 

 osmosis, P. Chatelain {Rec. Med. Y6t., 92 {1916), No. 13, pp. 393-397).— The 

 author describes a procedure for wound treatment in wliich either powdered 

 sodium chlorid or a solution of suitable strength of the salt is used as a dress- 

 ing. By this treatment the wound becomes naturally saturated with the 

 blood serum. 



The results of the new treatment indicate that the use of sodium chlorid is 

 superior to the use of either boric or picric acid. Suppuration is checked im- 

 mediately and cicatrization is rapid and complete. 



The specific serum treatment of wounds, E. Leclainche and H. Vall^e 

 (Rev. G&n. M6d. V6t., 25 {1916), No. 295, pp. 306-316) .—This is a general dis- 

 cussion of the treatment of wounds with polyvalent sera either by injection or 

 direct local application as recently introduced by the authors. 



The destruction of anthrax spores in hides and skins by caustic soda, 

 E. Haileb {Arb. K. Osndhtsamt., 50 {1915), No. 1, pp. 96-121).— A 0.5 to 1 

 per cent solution of caustic soda at a temperature of 15 to 20° C. (59 to 68° F.) 

 was found to destroy anthrax spores in cattle hides and sheep and goat skins. 

 The germicidal action of the solution was increased by the addition of a 5 to 

 10 per cent solution of sodium chlorid, the spores being destroyed in 72 hours 

 in almost all the cattle hides and sheep skins tested. 



Experimental studies on the immunity of foot-and-mouth disease, C. Tebni 

 {Clin. Vet. [J/tZan], Rass. Pol. Sanit. e Ig., 39 {1916), No. 9, pp. 257-261).— The 

 author has found that the virus of foot-and-mouth disease can be preserved in- 

 definitely by the passage of virulent blood, as well as the product of the local 

 lesions, through sensitized animals. The best procedure for conserving the 

 virulence and controlling an active infection of the virus was found to be the 

 use of infective material from the blood of an animal in a high febrile condi- 

 tion or the product of the local lesions. Other species of animals harbor the 

 virus of the disease through various periods of time without manifesting any 

 external symptoms. With the blood preserved in a thermostat after being at- 

 tenuated by cooling a resistance to the disease can be obtained by the successive 

 inoculation of the virus which is much greater than that manifested by animals 

 which have survived a severe case of the disease. The blood serum of animals 

 which have survived the disease possesses remarkable prophylactic properties 

 against the virus, and the inoculation of such blood containing the maximum 

 amount of antibodies causes a rapid recovery of animals in advanced stages of 

 the disease. Practical serotherapy thus seems to be possible. 



Two forms of immunity are distinguished, a general immunity localized in 

 the blood, especially in the white corpuscles (eosinophils?), red corpuscles, and 

 plasma, and another localized in the protective epithelium. The latter is indi- 

 cated as being the most permanent. 



The clinical form of the disease varies in degree according to the previously 

 existing immunity. On post-mortem examination of animals which had died 

 from the disease the virus was found to be localized in different organs, espe- 

 cially in the cardiac muscles, brain, liver, and kidneys. Less was found in the 

 spleen and in the bone marrow. 



In the epithelial lesions two substances were found ( granulo-stimoline and 

 granulo-lysin ) which are indicated as possessing chemotactic properties which 

 produce an eosinophilia. 



Tuberculosis of the seminal vesicles, vas deferens, and urethra in the 

 bovine, P. Cuxvsst {Rec. MM. Y6t., 92 {1916), No. IS, pp. 397-^08, figs. 3).— 

 The author reports a case and describes the lesions and histopathological find- 

 ings. The probable route of infection in the case reported and similar ones is 

 discussed. 



