288 EXPERIMENT STATION BECOED. 



"The virus hogs were kept in regulation virus pens 8 by 10 ft., elevated 18 

 in. from the ground on 4 legs, with waterproof metal-lined floor, slant roof, 

 both sides solid, small nari-ow dropdoor for ventilation in back, with door and 

 2 windows in front. Each pen is equipped with a wooden feeding trough and 

 card holder to accommodate a card for each hog. The pens are placed in 2 

 rows of 5 each, from 4 to 5 ft. apart. The 2 rows are separated by a fenced 

 alley approximatelj-^ 10 ft. wide. The group of pens in turn is surrounded by 

 a fence which prevents all communication from pen to pen except by the door- 

 way of each pen." 



Not all of the strains were continually passed through the susceptible animals, 

 and 6 strains at the utmost were used at any one time. "A strain passed through 

 hogs during a number of separate but not consecutive months, was injected 

 into not less than one lot of hogs each month and during that mouth the strain 

 may have been passed through 2 or more hogs." 



In some cases the injections were given for 13 months. With one exception 

 all the strains showed a gradual increase in virulence, and were capable of 

 producing, when arriving at the fixed stage, the first symptoms of hog cholera 

 on the fifth or sixth day, with death resulting on the seventh or eighth day. 

 From 2 to 5 cc. of the virus was given. The virus collected from these hogs 

 was used for hyperimmunizing 1,181 hogs, of which only 6.7 per cent received 

 one or more intraperitoneal injections, and 2.7 per cent one or more sub- 

 cutaneous injections. 



A typhoid-like disease in rabbits caused by Bacillus suipesticus, with 

 particular reference to the clinical course and prophylactic vaccination, 

 T. Obdway, E. Kellert. and F. P. Huested {Jour. Med. Research, 2S {1913), 

 No. 1. pp. Jfl-IO, pi. 1, figs. 9). — A clinical and pathological study of this 

 disease. 



Bacillary white diarrhea of young chicks, L. F. Rettger, W. F. Kirk- 

 PATRiCK, and F. H. Stoneburn {Connecticut Storrs Sta. Bui. JJ/, pp. 153-185, 

 Pis. 2, figs. ,9).— This third report on the subject (E. S. R., 25, p. 590) presents 

 some of the more important results which have been obtained during the past 

 2 years in investigations carried on at the Connecticut Storrs Station. 



It has been found that the period of greatest danger from bacillary white 

 diarrhea lies within the first 48 hours, but that chicks may acquire the disease 

 up to the time they are 4 days old. " Hens may become bacillus carriers after 

 they have reached maturity. The ovaries may become infected by contact of 

 the hens with infected hens, or by artificial infection of the litter. The in- 

 fection is, in all probability, acquired through the mouth. 



" The feeding of sour milk to chicks appears to be a good means of pre- 

 venting, or at least holding in check, epidemics of bacillary white diarrhea. 

 Hence, whenever it is impossible or impracticable at once t(f introduce new 

 stock, sour milk maj' be an important agent in lessening the dangei's of great 

 loss from the disease. The sour milk should be fed early; furthermore, it 

 should be kept before the chicks constantly. Sour milk has an important 

 stimulating effect on the growth and vitality of chicks, and for this reason 

 alone it is a most valuable food. 



" For the complete elimination of white diarrhea from a poultry farm it is 

 necessary to reject for breeding purposes stock which harbors white diarrhea 

 infection, and to obtain eggs or live stock from sources where white diarrhea 

 infection has not been known to exist. It should be considered both a moral 

 and legal ofiense for persons to sell or exchange eggs, chicks, or ma^^ure stock 

 which come from flocks that they know to be infected with the germ of 

 bacillary white diarrhea. 



